Results 61 to 70 of about 4,859,991 (300)

The Landscape of Microbial Composition and Associated Factors in Pancreatic Ductal Adenocarcinoma Using RNA-Seq Data

open access: yesFrontiers in Oncology, 2021
Recent research studies on interrogation of the tumor microbiome (including bacteria, viruses, and fungi) have yielded important insights into the role of microbes in carcinogenesis, therapeutic responses, and resistance.
Dong Yu   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Plasma Levels of Interleukin 2 (IL-2) Associated with Hearing Loss Evaluation in the Elderly

open access: yesNoise and Health
Context: Presbycusis can be mediated by the effects of inflammatory processes on the auditory system, and these aging biological mechanisms remain poorly studied.
Fernanda P. Cordeiro   +4 more
doaj   +1 more source

Adipose Tissue and Biological Factors. Possible Link between Lymphatic System Dysfunction and Obesity

open access: yesMetabolites, 2021
The World Health Organization (WHO) has recognised obesity as one of the top ten threats to human health. Obesity is not only a state of abnormally increased adipose tissue in the body, but also of an increased release of biologically active metabolites.
Klaudia Antoniak   +3 more
doaj   +1 more source

Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework [PDF]

open access: yes, 2010
We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings.
De Raedt, Rudi, Koster, Ernst
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Patterns of Factors in the National Institute on Aging Health Disparities Research Framework Domains and Mild Cognitive Impairment Risk

open access: yesAJPM Focus
Introduction: Alzheimer's disease and related dementias are public health and social care challenges. This study used the National Institute on Aging Health Disparities Research Framework to organize potential cognitive impairment risk factors.
Maria Vassilaki, MD, PhD   +13 more
doaj   +1 more source

Resuscitation-promoting factors possess a lysozyme-like domain [PDF]

open access: yes, 2004
The novel bacterial cytokine family – resuscitation-promoting factors (Rpfs) – share a conserved domain of uncharacterized function. Predicting the structure of this domain suggests that Rpfs possess a lysozyme-like domain.
Cohen Gonsaud, M.   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An Assessment of Gypsy Moth Eradication Attempts in Michigan (Lepidoptera: Lymantriidae) [PDF]

open access: yes, 2017
Michigan\u27s infestation of gypsy moth, Lymantria dispar, extends over 600,000 acres, First discovered in Michigan in the 19505, gypsy moth was reportedly eradicated through the use of DDT then reintroduced in the 1970s, Substantial circumstantial ...
Dreistadt, Steve H
core   +3 more sources

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