Results 121 to 130 of about 10,240,076 (319)
Annual Report - Marine Biological Laboratory, 1917
, 1918 Annual report of the Marine Biological Laboratory in Woods Hole. 1917.
Marine Biological Laboratory (Woods Hole MA)
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1965
, 1966 Annual report of the Marine Biological Laboratory in Woods Hole. 1965.
Marine Biological Laboratory (Woods Hole MA)
core
iScienceSummary: Oxidative stress disrupts signaling pathways contributing to chronic diseases, while the KEAP1-NRF2 pathway is central to cellular antioxidant defenses. Current synthetic antioxidants struggle to activate this pathway efficiently or selectively.
Mingyue Yuwen +6 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1944
, 1945 Annual report of the Marine Biological Laboratory in Woods Hole. 1944.
Marine Biological Laboratory (Woods Hole MA)
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1910
, 1911 Annual report of the Marine Biological Laboratory in Woods Hole. 1910.
Marine Biological Laboratory (Woods Hole MA)
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Journal of Functional Morphology and KinesiologyBackground: Whole-body electromyostimulation (WB-EMS) combines full-body electrical muscle stimulation with instructor-assigned exercise. Electrical impulses are transmitted to the peripheral muscles through electrodes applied to the body.
Valentina Grgic +4 more
doaj +1 more source