Results 181 to 190 of about 10,240,076 (319)

The Sentinel Sleep Theory: Unweaving the biological function of REM sleep. [PDF]

Sleep Med X
Spinassi RB.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1896-1902

, 1902
Annual report of the Marine Biological Laboratory in Woods Hole for the years 1896-1899.
Marine Biological Laboratory (Woods Hole MA)
core  

Life as Counterfactual Geometry: An Adversarial Theory of Biological Function. [PDF]

Entropy (Basel)
Buzea CG, Nedeff F, Mirilă D, Nedeff V, Agop M, Ochiuz L, Dobreci L, Vasincu D.   +7 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1961

, 1960
Annual report of the Marine Biological Laboratory in Woods Hole. 1961.
Marine Biological Laboratory (Woods Hole MA)
core  

Epigenetic dysregulation and biological function of PDX1 in prostate cancer. [PDF]

Oncotarget
Adeyika TA, Datturgi A, Ettinoffe Y, Ghosh S, Albanese C, Kwabi-Addo B.   +5 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1915

, 1912
Annual report of the Marine Biological Laboratory in Woods Hole. 1915.
Marine Biological Laboratory (Woods Hole MA)
core  

From Localization to Coordination: Distributed Causality and the Emergence of Biological Function in the Brain and Plant Systems. [PDF]

Biology (Basel)
Castiello U.
europepmc   +1 more source