Uncovering latent biological function associations through gene set embeddings. [PDF]
Huang Y, Zhong F, Liu L.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Clinical significance and biological function of PRKCQ-AS1/miR-582-3p expression in LUAD. [PDF]
Liu L +5 more
europepmc +1 more source
Mechanism of Action of Resveratrol Affecting the Biological Function of Breast Cancer Through the Glycolytic Pathway. [PDF]
Gao Y +9 more
europepmc +1 more source
Fibulin1 as a Novel Target for Promoting the Biological Function of Bone Marrow Mesenchymal Stem Cells and Implant Osseointegration in Diabetic Patients. [PDF]
Zhang Y +6 more
europepmc +1 more source
Recent research advances in the biological function and molecular mechanism of methylmalonic acid. [PDF]
Wang Z +6 more
europepmc +1 more source
Prognostic value and potential biological function of PMSD11 in lung adenocarcinoma. [PDF]
Xi Y +6 more
europepmc +1 more source
Biological function of RNA-binding proteins in myocardial infarction: a potential emerging therapeutic limelight. [PDF]
Jin C +12 more
europepmc +1 more source
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The relativity of biological function
Theory in Biosciences, 2015Function is a central concept in biological theories and explanations. Yet discussions about function are often based on a narrow understanding of biological systems and processes, such as idealized molecular systems or simple evolutionary, i.e., selective, dynamics.
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Biological Functions of Plasmalogens
2020Plasmalogens (Pls) are one kind of phospholipids enriched in the brain and other organs. These lipids were thought to be involved in the membrane bilayer formation and anti-oxidant function. However, extensive studies revealed that Pls exhibit various beneficial biological activities including prevention of neuroinflammation, improvement of cognitive ...
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