Results 211 to 220 of about 2,475,642 (267)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Mechanism of Action of Resveratrol Affecting the Biological Function of Breast Cancer Through the Glycolytic Pathway. [PDF]

World J Oncol
Gao Y, Wang YY, Wang BD, Hu QY, Jiang JR, Feng B, Gao XL, Liu LK, Zhu WB, Yue LL.   +9 more
europepmc   +1 more source

Uncovering latent biological function associations through gene set embeddings. [PDF]

BMC Bioinformatics
Huang Y, Zhong F, Liu L.
europepmc   +1 more source

Fibulin1 as a Novel Target for Promoting the Biological Function of Bone Marrow Mesenchymal Stem Cells and Implant Osseointegration in Diabetic Patients. [PDF]

Int Dent J
Zhang Y, Jia F, Li K, Yan Y, Liu X, Geng W, Liang C.   +6 more
europepmc   +1 more source

Biological function of RNA-binding proteins in myocardial infarction: a potential emerging therapeutic limelight. [PDF]

Cell Biosci
Jin C, Ye Y, Gao L, Zhong Z, Zhou C, Wu X, Li X, Zhou G, Chen S, Wei Y, Cai L, Liu S, Xu J.   +12 more
europepmc   +1 more source

Prognostic value and potential biological function of PMSD11 in lung adenocarcinoma. [PDF]

J Thorac Dis
Xi Y, Zeng J, Zhou Y, Shen W, Taniguchi H, Rajandram R, Krishnasamy S.   +6 more
europepmc   +1 more source

The biological function of Atractylodes lancea and its application in animal husbandry: a review. [PDF]

Front Vet Sci
Gao Y, Wang D, Ma X, Li J, Wang D, Chen B, Yang X, Leng H.   +7 more
europepmc   +1 more source

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The relativity of biological function

Theory in Biosciences, 2015
Function is a central concept in biological theories and explanations. Yet discussions about function are often based on a narrow understanding of biological systems and processes, such as idealized molecular systems or simple evolutionary, i.e., selective, dynamics.
Manfred D Laubichler, Peter F Stadler, Sonja J Prohaska   +2 more
exaly   +5 more sources