Results 81 to 90 of about 10,240,076 (319)
Annual Report - Marine Biological Laboratory, 2002
Annual report of the Marine Biological Laboratory in Woods Hole. 2002.
Marine Biological Laboratory (Woods Hole MA)
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1988
Annual report of the Marine Biological Laboratory in Woods Hole. 1988.
Marine Biological Laboratory (Woods Hole MA)
core
ON BIOLOGICAL OXIDATIONS AS FUNCTION OF TEMPERATURE [PDF]
1. The critical thermal increments are calculated for respiratory processes (O2 consumption, CO2 production) in various plants and animals. They are characteristically found to be of two, possibly three, types: µ = 11,500, and 16,100 or 16,700. The first is commonly encountered above 15°, the second below that temperature, but these relations may be ...
openaire +2 more sources
Effect of L-DOPA/Benserazide on Propagation of Pathological α-Synuclein
Parkinson’s disease (PD) and related disorders are characterized by filamentous or fibrous structures consisting of abnormal α-synuclein in the brains of patients, and the distributions and spread of these pathologies are closely correlated with disease ...
Aki Shimozawa +9 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1935
Annual report of the Marine Biological Laboratory in Woods Hole. 1935.
Marine Biological Laboratory (Woods Hole MA)
core
Protein functions and biological contexts
The availability of a rough draft of the predicted human proteome allows an evaluation of the extent to which the predicted and biochemical functions of proteins are in alignment, and the roles of different technologies and approaches to understanding human diseases and instantiating therapeutics.
Miklos, George L, Maleszka, Ryszard
openaire +2 more sources
Structure-guided screening identifies Tucatinib as dual inhibitor for MCT1/2
Cell surface glycoproteins Basigin or embigin form heterodimers with monocarboxylate transporters (MCTs), enhancing their membrane trafficking and modulating their transport functions.
Binghong Xu +10 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source

