Results 181 to 190 of about 26,915 (297)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Uncovering the role of chemical pollutants in shaping biological invasions. [PDF]

Proc Biol Sci
Ligocki IY, Brand JA, Thoré ESJ, Aich U, Brodin T, Camacho-Cervantes M, Martin JM, Munson A, Polverino G, Wong BBM, Bertram MG.   +10 more
europepmc   +1 more source

Global environmental changes more frequently offset than intensify detrimental effects of biological invasions. [PDF]

Proc Natl Acad Sci U S A, 2022
Lopez BE, Allen JM, Dukes JS, Lenoir J, Vilà M, Blumenthal DM, Beaury EM, Fusco EJ, Laginhas BB, Morelli TL, O'Neill MW, Sorte CJB, Maceda-Veiga A, Whitlock R, Bradley BA.   +14 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Dynamic miRNA-host gene co-expression and functional regulation in response to salinity fluctuations during biological invasions. [PDF]

Mar Life Sci Technol
Yan W, Fu R, Huang X, Shenkar N, Zhan A.
europepmc   +1 more source

American fall webworm in China: A new case of global biological invasions. [PDF]

Innovation (Camb), 2022
Ning J, Lu P, Fan J, Ren L, Zhao L.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Genomic Insights Into Early-Stage Selective Filtering During the Transport Stage of Biological Invasions. [PDF]

Evol Appl
Chen Y, Fu R, Zhan A.
europepmc   +1 more source

Advancing One Biosecurity to Address the Pandemic Risks of Biological Invasions. [PDF]

Bioscience, 2021
Hulme PE.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source