Results 41 to 50 of about 26,915 (297)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Horticultural markets promote alien species invasions : an Estonian case study of herbaceous perennials [PDF]

, 2013
Gardening is a popular pastime, but commercial horticulture is responsible for the introduction of alien species and contributes to invasions in a variety of ways.
Merle Ööpik, Bunce,Robert G.H. Bunce, Ööpik,Merle, Bunce, R. G. H., Ööpik, Merle, 6\uf6pik, Merle, Bunce, Robert G.H. Bunce, Bunce, Robert G. H., Monika Tischler, Tischler, Monika, Robert G.H. Bunce Bunce, Tischler,Monika   +11 more
core   +1 more source

The Relative Growth of Invasive Solanum rostratum Dunal Decreases with Increasing Competitive Species Richness Regardless of Resource Conditions

Plants
The biotic resistance hypothesis proposes that species-rich communities are more resistant to biological invasions due to the less available resources for invaders. The variation in available soil resources may affect the invasion resistance of community,
Fa-Zhao Qi, Xiu-Rong Lu, Dong-Pu Wu, Xiao-Jia Zhang, Ying Gao, Lin Geng, Ming-Chao Liu, Yu-Long Feng   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The role of eco-evolutionary experience in invasion success

, 2013
Invasion ecology has made considerable progress in identifying specific mechanisms that potentially determine success and failure of biological invasions.
Saul, Wolf-Christian, Jeschke, Jonathan M., Jonathan Jeschke, Heger, Tina, Saul,Wolf-Christian, Tina Heger, Jeschke,Jonathan M., Jeschke, Jonathan, Wolf-Christian Saul, Heger,Tina   +9 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Biological invasions undermine the functional diversity of fish community in a large subtropical river

, 2018
Biological invasions are considered to be one of the main threats to biodiversity. Invasions lead to a loss of native species, changes to species composition, and a shift in the functioning and stability of ecosystems.
Tian Zhao, Zhao, Tian, Xinhui Li, Fangmin Shuai, Sovan Lek, Shuai, Fangmin, Lek, Sovan, Li, Xinhui   +7 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Food Source and Gut Bacteria Show Effects on the Invasion of Alien Pests—A Case of Bactrocera dorsalis (Hendel) (Diptera: Tephritidae)

Insects
How alien pests invade new areas has always been a hot topic in invasion biology. The spread of the Bactrocera dorsalis from southern to northern China involved changes in food sources. In this paper, in controlled conditions, we take Bactrocera dorsalis
Yanfei Zhu, Rui Han, Tong Zhang, Jiawen Yang, Ziwen Teng, Yinjun Fan, Pengdong Sun, Yongyue Lu, Yonglin Ren, Fanghao Wan, Hongxu Zhou   +10 more
doaj   +1 more source