Results 121 to 130 of about 1,599,536 (288)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Dynamics of an Open Access: The case of the Baltic Sea Cod Fishery - A Strategic Approach - [PDF]

open access: yes
The paper sets up a discrete-time, deterministic model of a single industry, in the light of the benchmark theory of Smith (1968). The model is used to de-scribe the dynamics of recovery from a replenishable resource such as the case of the eastern ...
Lone Grønbæk Kronbak
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Le problème des limites à la procréation assistée dans les lois des principaux pays européens

open access: yesDroit et Cultures, 2006
This study of assisted reproduction limits in legislation of the main European countries raises various issues. The first one is to know whether assisted reproduction should be an individual choice or be reserved for therapeutic purpose.
Paolo Zatti
doaj  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Biological bases for the revision of dose limits to the eye lens

open access: yesJournal of Medical Physics, 2016
Srinivasa Badanidiyoor Rao
doaj   +1 more source

Spectrophotometric Determination of Cefazolin in Mixed Saliva of Practically Healthy Subjects and Patients with Infective Somatic Pathology

open access: yesАнтибиотики и Химиотерапия, 2020
The behaviour of cefazolin in aqueous and biological media with varying the antibiotic concentration was studied by UV-spectroscopy. Range of the contents and the detection limits of cefazolin were determined.
E. G. Kulapina   +3 more
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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