Results 81 to 90 of about 1,599,536 (288)
Cadernos de Saúde Pública, 1996 In general, biological exposure limits are only used for the promotion and preservation of workers' health and are not applied for diagnostic purposes. However, the issue is controversial for certain types of occupational poisoning.
Cordeiro Ricardo
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
eLife, 2018 The hepatitis B virus capsid represents a promising therapeutic target. Experiments suggest the capsid must be flexible to function; however, capsid structure and dynamics have not been thoroughly characterized in the absence of icosahedral symmetry ...
Jodi A Hadden +5 more
doaj +1 more source
New approaches to the exploration: planet Mars and bacterial life
, 2011 Planet Mars past environmental conditions were similar to the early Earth, but nowadays they are similar to those of a very cold desert, irradiated by intense solar UV light. However, some terrestrial lifeform showed the capability to adapt to very harsh
Bertoloni, Giulio +2 more
core
Die lage der Fischbestände in Nordostatlantik, Nord- und Ostsee. Einschätzungen des Internationalen Rates für Meeresforschung im Frühjahr 2000 [PDF]
, 2000 The spring session of ACFM gave advice for a number of stocks in the North Atlantic, North Sea and Baltic. The present assessment of the situation is given here for stocks of higher importance for the German fishery.
Gröhsler, Tomas +2 more
core
Biological Monitoring Without Limits [PDF]
Annals of Work Exposures and Health, 2017 John, Cocker, Kate, Jones
openaire +2 more sources
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Scientific ReportsPlant growth and high yields are secured by intensive use of nitrogen (N) fertilizer, which, however, pollutes the environment, especially when N is in the form of nitrate.
Christian W. Kuppe, Johannes A. Postma
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source