Results 41 to 50 of about 453,892 (296)

Measurement in biological systems from the self-organisation point of view

open access: yes, 2015
Measurement in biological systems became a subject of concern as a consequence of numerous reports on limited reproducibility of experimental results.
A.K. Dewdney   +13 more
core   +1 more source

Modules identification in gene positive networks of hepatocellular carcinoma using pearson agglomerative method and Pearson cohesion coupling modularity [PDF]

open access: yes, 2012
In this study, a gene positive network is proposed based on a weighted undirected graph, where the weight represents the positive correlation of the genes.
Gao, Zhiwei, Hu, Jinyu
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Mathematical modeling of biological systems [PDF]

open access: yesBioelectrochemistry and Bioenergetics, 1979
This two-volume, interdisciplinary work is a unified presentation of a broad range of state-of-the-art topics in the rapidly growing field of mathematical modeling in the biological sciences. Highlighted throughout both works are mathematical and computational approaches to examine central problems in the life sciences, ranging from the organizational ...
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Assessing the role of online mathematics tools in enhancing student learning and engagement

open access: yesEducational Technology Quarterly
As digital technology improves and educational standards rise, online tools for teaching mathematics are one of the advancements recorded in digital technologies.
Olajumoke Olayemi Salami   +1 more
doaj   +1 more source

Mathematics for Biological Scientists

open access: yesJournal of Anatomy, 2010
Biologists need tools to do their work, and they need to understand their tools. This catch-up text is designed for a 100-level introductory course that ensures students of biology have an adequate mathematical grounding to continue in their tertiary education.
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Research-driven education: An introductory course to systems and synthetic biology

open access: yesFrontiers in Systems Biology, 2022
Systems and Synthetic Biology are complementary fields emerging side-by-side into mainstream scientific research. Whilst systems biologists focus on understanding natural systems, synthetic biologists wish to modify, adapt and re-purpose biological ...
Robert W. Smith   +5 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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