Results 41 to 50 of about 3,996,815 (308)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Genome sequence of bacteriophage AmiCi24 isolated using Arthrobacter globiformis

open access: yesmicroPublication Biology
AmiCi24 is a novel siphoviral bacteriophage that was isolated from a soil sample collected in Sewell, NJ, USA using Arthrobacter globiformis B-2979 as the host. AmiCi24 has a genome consisting of 38,466 base pairs that encodes 68 predicted protein-coding
Paige Baldwin   +15 more
doaj   +1 more source

Can Mathematics be Biology's next microscope in disease research at the interface?

open access: yesBiomath, 2017
In this paper we discuss how mathematics can be integrated into biological research as well as the benefits and challenges related to this process. The focus is on the research of diseases at the interface between wildlife, humans and livestock with some
Roumen Anguelov, Armanda Bastos
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Department of Applied Mathematics and Statistics newsletter, September 11, 2023

open access: yes, 2023
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Māori medium children’s views about learning mathematics: possibilities for future directions [PDF]

open access: yes, 2011
Pre-European traditional Māori education in New Zealand was integrated and holistic. With Western influence many Maori children struggled to achieve at school. Māori medium education based on retaining Māori values, language and culture therefore emerged
Taylor, Merilyn, Hāwera, Ngārewa
core  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Assessing the role of online mathematics tools in enhancing student learning and engagement

open access: yesEducational Technology Quarterly
As digital technology improves and educational standards rise, online tools for teaching mathematics are one of the advancements recorded in digital technologies.
Olajumoke Olayemi Salami   +1 more
doaj   +1 more source

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