Results 41 to 50 of about 92,910 (256)

Assessing the role of online mathematics tools in enhancing student learning and engagement

Educational Technology Quarterly
As digital technology improves and educational standards rise, online tools for teaching mathematics are one of the advancements recorded in digital technologies.
Olajumoke Olayemi Salami, Erica Dorethea Spangenberg   +1 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Associations between biological maturation, physical performance, postural control, and mathematical achievement in youth soccer players.

PLoS ONE
This investigation explored relationships between biological maturation, physical and academic performance in young male soccer players. Thirty-eight players (age: 9.79 ± 1.21 years; body mass index (BMI): 20.4 ± 2.39 kg/m2; body fat: 16.8 ± 2.21 ...
Souhail Hermassi, Ferman Konukman, Senaid Salem Al-Marri, Lawrence D Hayes, Thomas Bartels, René Schwesig   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Fus3‐triggered Tec1 degradation modulates mating transcriptional output during the pheromone response

Molecular Systems Biology, 2008
The yeast transcription factor Ste12 controls both mating and filamentation pathways. Upon pheromone induction, the mitogen‐activated protein kinases, Fus3 and Kss1, activate Ste12 by relieving the repression of two functionally redundant Ste12 ...
Song Chou, Su Zhao, You Song, Haoping Liu, Qing Nie   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Research-driven education: An introductory course to systems and synthetic biology

Frontiers in Systems Biology, 2022
Systems and Synthetic Biology are complementary fields emerging side-by-side into mainstream scientific research. Whilst systems biologists focus on understanding natural systems, synthetic biologists wish to modify, adapt and re-purpose biological ...
Robert W. Smith, Luis Garcia-Morales, Luis Garcia-Morales, Vitor A. P. Martins dos Santos, Vitor A. P. Martins dos Santos, Edoardo Saccenti   +5 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Assessment of Environmental Sustainability in Ecotourism at Tanaka Waterfall, Mount Kawi, Malang, Indonesia [PDF]

BIO Web of Conferences
This study examines the ecotourism features in the Tanaka Waterfall area of Mount Kawi. It focuses on attractions, access, facilities, and local organizations to help improve tourism for the community and protect the environment.
Mukaromah Salsabilatul, Zayadi Hasan
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source