Results 31 to 40 of about 116,480 (161)

A promising drug delivery candidate (CS-g-PMDA-CYS-fused gold nanoparticles) for inhibition of multidrug-resistant uropathogenic Serratia marcescens

Drug Delivery, 2020
Antibiotic resistance amongst microbial pathogens is a mounting serious issue in researchers and physicians. Various alternatives to overcome the multidrug-resistant bacterial infections are under search, and biofilm growth inhibition is one of them.
Ping Shi, Rajendran Amarnath Praphakar, Sadhasivan Deepa, Kannan Suganya, Prashant Gupta, Riaz Ullah, Ahmed Bari, Marudhamuthu Murugan, Mariappan Rajan   +8 more
doaj   +1 more source

The Oxepane Motif in Marine Drugs

Marine Drugs, 2017
Oceans have shown to be a remarkable source of natural products. The biological properties of many of these compounds have helped to produce great advances in medicinal chemistry.
Héctor Barbero, Carlos Díez-Poza, Asunción Barbero   +2 more
doaj   +1 more source

Advanced Therapy Medicinal Products (ATMP)and exemptions to the Regulation 1394/2007: how confident can we be? An exploratory analysis.

Frontiers in Pharmacology, 2012
The market authorisation procedure for medicinal products for human use is relying on their demonstrated efficacy, safety and pharmaceutical quality. This applies to all medicinal products whether of chemical or biological origin. Since October 2009, the
Philippe eVan Wilder
doaj   +1 more source

Safety of Biological Medicinal Products for Hereditary Coagulopathies: An Analysis of the Russian Pharmacovigilance Database

Безопасность и риск фармакотерапии
INTRODUCTION. With the expanding product range and the introduction of novel biological medicinal products for haemophilia A, haemophilia B, and von Willebrand disease in the Russian pharmaceutical market, post-marketing safety surveillance becomes ...
D. S. Fokina, O. V. Zhukova, A. L. Khokhlov   +2 more
doaj   +1 more source

A Regulatory Perspective on Biosimilar Medicines

Pharmaceutics
By definition, biosimilar medicinal products are biological medicinal products that are similar to other biological medicinal products that are already on the market—the reference medicinal products.
Marta Agostinho Cordeiro, Carla Vitorino, Carlos Sinogas, João J. Sousa   +3 more
doaj   +1 more source

Safety, dosing, and pharmaceutical quality for studies that evaluate medicinal products (including biological products) in neonates [PDF]

Pediatric Research, 2016
The study of medications among pediatric patients has increased worldwide since 1997 in response to new legislation and regulations, but these studies have not yet adequately addressed the therapeutic needs of neonates. Additionally, extant guidance developed by regulatory agencies worldwide does not fully address the specificities of neonatal drug ...
Ward, RM, Benjamin, D, Barrett, JS, Allegaert, Karel, Portman, R, Davis, J M, Turner, MA, Inc,   +7 more
openaire   +4 more sources

Genotyping problems of microorganisms

Биопрепараты: Профилактика, диагностика, лечение, 2018
Genotyping efficiency depends on resolution of methods which provided by the target sequence of genome, efficiency of enzymes, primers and conditions of DNA restriction and PCR amplification.
R. A. Volkova, E. S. Skolotneva, E. V. Elbert, E. D. Mytsa, D. S. Davydov, A. A. Movsesyants, V. A. Merkulov, V. P. Bondarev, I. V. Borisevich   +8 more
doaj  

Characteristics of Morbidity of the Tick-Borne Encephalitis in Vaccinated

Эпидемиология и вакцинопрофилактика, 2020
Relevance. Vaccination against the tick-borne encephalitis (TBE), during the mass immunization, by using modern vaccines provides high epidemiological effect (98–99%); however, there are known cases of incidents among vaccinated population.
V. V. Pogodina, M. S. Scherbinina, N. M. Kolyasnikova, S. G. Gerasimov, T. V. Slezkina, J. P. Sanchez-Pimentel, A. A. Ishmuhametov   +6 more
doaj   +1 more source

Development of an Approach to the Assessment of Changes to Approved Biological Products

Биопрепараты: Профилактика, диагностика, лечение, 2019
The need to strengthen the post-approval regulation of biological products stems from their increasing role in the treatment of serious human diseases.
E. V. Petraneva, I. A. Proskurina, D. V. Goryachev, E. L. Kovaleva   +3 more
doaj   +1 more source

Genome-wide characterization of the HpHsf gene family and expression analysis under heat stress in Herpetospermum pedunculosum

Frontiers in Plant Science
IntroductionHeat shock transcription factors (Hsfs) are key regulators of plant responses to heat stress and other environmental challenges. However, the Hsf gene family of Herpetospermum pedunculosum, an alpine medicinal plant valued for its ...
Ziwei Zhu, Ziwei Zhu, Ziwei Zhu, Haijing Liang, Haijing Liang, Haijing Liang, Min Sun, Min Sun, Min Sun, Yixi Yang, Yixi Yang, Yixi Yang, Xiaoying Qin, Qi Zhao, Qi Zhao, Qi Zhao, Rui Li, Rui Li, Rui Li, Yang Tao, Yang Tao, Yang Tao   +21 more
doaj   +1 more source