Results 101 to 110 of about 4,949,866 (357)

Local Dot Motion, Not Global Configuration, Determines Dogs’ Preference for Point-Light Displays

Animals, 2019
Visual perception remains an understudied area of dog cognition, particularly the perception of biological motion where the small amount of previous research has created an unclear impression regarding dogs’ visual preference towards different ...
Carla J. Eatherington, Lieta Marinelli, Miina Lõoke, Luca Battaglini, Paolo Mongillo   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Deep learning cardiac motion analysis for human survival prediction [PDF]

, 2018
Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient ...
Bello, Ghalib A., Biffi, Carlo, Cook, Stuart A., Dawes, Timothy J. W., de Marvao, Antonio, Duan, Jinming, Gibbs, J. Simon R., Howard, Luke S. G. E., O'Regan, Declan P., Rueckert, Daniel, Wilkins, Martin R.   +10 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Decoding the physics of observed actions in the human brain

eLife
Recognizing goal-directed actions is a computationally challenging task, requiring not only the visual analysis of body movements, but also analysis of how these movements causally impact, and thereby induce a change in, those objects targeted by an ...
Moritz F Wurm, Doruk Yiğit Erigüç
doaj   +1 more source

Brain responses to biological motion predict treatment outcome in young children with autism

Translational Psychiatry, 2016
Autism spectrum disorders (ASDs) are common yet complex neurodevelopmental disorders, characterized by social, communication and behavioral deficits. Behavioral interventions have shown favorable results—however, the promise of precision medicine in ASD ...
D. Y. Yang, K. Pelphrey, D. Sukhodolsky, Michael J. Crowley, Eran Dayan, N. Dvornek, Archana Venkataraman, James S. Duncan, Lawrence H. Staib, Pamela Ventola   +9 more
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Perception of animate motion in dogs

Frontiers in Psychology
Various motion cues can lead to the perception of animacy, including (1) simple motion characteristics such as starting to move from rest, (2) motion patterns of interactions like chasing, or (3) the motion of point-lights representing the joints of a ...
Judit Abdai
doaj   +1 more source

Flocking and turning: a new model for self-organized collective motion [PDF]

, 2014
Birds in a flock move in a correlated way, resulting in large polarization of velocities. A good understanding of this collective behavior exists for linear motion of the flock.
Cavagna, Andrea, Del Castello, Lorenzo, Giardina, Irene, Grigera, Tomas, Jelic, Asja, Melillo, Stefania, Mora, Thierry, Parisi, Leonardo, Silvestri, Edmondo, Viale, Massimiliano, Walczak, Aleksandra M.   +10 more
core   +4 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source