Results 111 to 120 of about 2,000,131 (360)
TopologyNet: Topology based deep convolutional neural networks for biomolecular property predictions
, 2017 Although deep learning approaches have had tremendous success in image, video and audio processing, computer vision, and speech recognition, their applications to three-dimensional (3D) biomolecular structural data sets have been hindered by the ...
Cang, Zixuan, Wei, Guo-Wei
core +2 more sources
Nature Communications, 2020 Perception is thought to be shaped by the environments for which organisms are optimized. These influences are difficult to test in biological organisms but may be revealed by machine perceptual systems optimized under different conditions.
Mark R. Saddler +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Building an artificial neural network with neurons
AIP Advances, 2019 Artificial neural networks are based on mathematical models of biological networks, but it is not clear how similar these two networks are. We have recently demonstrated that we can mechanically manipulate single neurons and create functioning synapses ...
M. Rigby +5 more
doaj +1 more source
Multitasking associative networks
, 2012 We introduce a bipartite, diluted and frustrated, network as a sparse restricted Boltzman machine and we show its thermodynamical equivalence to an associative working memory able to retrieve multiple patterns in parallel without falling into spurious ...
Adriano Barra +8 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Improved Learning Experience Memristor Model and Application as Neural Network Synapse
IEEE Access, 2019 This paper proposes a memristor model, named learning experience memristor (LEM), for using as synapse in the associative neural network. The properties of LEM are discussed under different external voltages.
Xiaohong Zhang, Keliu Long
doaj +1 more source
Biological constraints on neural network models of cognitive function
Nature Reviews Neuroscience, 2021 F. Pulvermüller +3 more
semanticscholar +1 more source
Biologically Plausible Artificial Neural Networks [PDF]
, 2013 Artificial Neural Networks (ANNs) are based on an abstract and simplified view of the neuron. Artificial neurons are connected and arranged in layers to form large networks, where learning and connections determine the network function. Connections can be formed through learning and do not need to be ’programmed.’ Recent ANN models lack many ...
openaire +2 more sources