Results 121 to 130 of about 2,000,131 (360)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Equivalence of Equilibrium Propagation and Recurrent Backpropagation
, 2018 Recurrent Backpropagation and Equilibrium Propagation are supervised learning algorithms for fixed point recurrent neural networks which differ in their second phase.
Bengio, Yoshua, Scellier, Benjamin
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Research on Lateral Inhibition Network Based on Cell Membrane Electrical Model
PhotonicsLateral inhibition is a prevalent occurrence within the biological neural system, enhancing the human brain’s ability to perceive edge information within a given scene.
Dao-Han Qi, Ming-Jie Sun, Qing-Zhong Cai
doaj +1 more source
Neural Network Analysis of Follow-Up Data in Primary Breast Cancer
The International Journal of Biological Markers, 2000 This paper reports on the performance of a recently developed neural network environment incorporating likelihood-based optimization and complexity reduction techniques in the analysis of breast cancer follow-up data with the goal of building up a ...
N. Harbeck MD, PhD +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
The effects of temperature on the dynamics of the biological neural network. [PDF]
J Biol Phys, 2022 Jabbari MB, Karamati MR.
europepmc +1 more source
Biologically-inspired training of spiking recurrent neural networks with neuromorphic hardware
, 2022 Thomas Bohnstingl +7 more
openalex +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source