Results 261 to 270 of about 1,932,979 (312)

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

MLGCN-Driver: a cancer driver gene identification method based on multi-layer graph convolutional neural network. [PDF]

BMC Bioinformatics
Wei PJ, Zhou J, Cao RF, Ding Y, Yue Z, Zheng CH.   +5 more
europepmc   +1 more source

Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In Vitro

Advanced Healthcare Materials, EarlyView.
An advanced on‐chip cortical network platform merges human stem cell‐derived neurons with microfabricated devices, enabling precise large‐format circuit design, optogenetic control, and molecular dissection of synaptic formation. This innovative system offers a powerful new tool to explore and model brain connectivity, disease mechanisms, can serve as ...
Pacharaporn Suklai, Taylor Minckley, Cathleen Hagemann, Karolina Faber, Rosalind Norkett, Ludovica Guetta, Kelly O'Toole, Bethany Geary, Michael J. Devine, Andrea Serio   +9 more
wiley   +1 more source

Deep learning approach to parameter optimization for physiological models. [PDF]

Biol Methods Protoc
Duan X, Periwal V.
europepmc   +1 more source

Inference and modeling of biological networks : a statistical-physics approach to neural attractors and protein fitness landscapes

, 2018
Lorenzo Posani
openalex   +1 more source

Novel approach for AI-based N2O emission reduction in biological wastewater treatment relying on genetic algorithms and neural networks

Arne Freyschmidt, Stephan Köster
openalex   +1 more source

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

Advanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Evaluating the effectiveness of the forest pests and diseases control methods on the industrial wood production using deep learning. [PDF]

Sci Rep
Sevinç V.
europepmc   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source