Results 81 to 90 of about 1,932,979 (312)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Modeling the infiltration rate of wastewater infiltration basins considering water quality parameters using different artificial neural network techniques

open access: yesEngineering Applications of Computational Fluid Mechanics, 2022
Predicting the infiltration rate (IR) of treated wastewater (TWW) is essential in controlling clogging problems. Most researchers that predict the IR using neural network models considered the characteristics parameters of soil without considering  those
Ghada Abdalrahman   +7 more
doaj   +1 more source

ElegansAI: how a biological neural network would compare with artificial networks? [PDF]

open access: gold, 2023
Francesco Bardozzo   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Ion‐specific effects in confined nanochannels and neural network

open access: yesAggregate, 2023
Since the discovery of biological ion channels and their role in physiology, scientists have been trying to create artificial structures that mimic biological ion channels.
Weichen Wei, Xuejiao Wang
doaj   +1 more source

A Neural Algorithm of Artistic Style

open access: yes, 2015
In fine art, especially painting, humans have mastered the skill to create unique visual experiences through composing a complex interplay between the content and style of an image.
Bethge, Matthias   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Scalable Implementation of Hippocampal Network on Digital Neuromorphic System towards Brain-Inspired Intelligence

open access: yesApplied Sciences, 2020
In this paper, an expanded digital hippocampal spurt neural network (HSNN) is innovatively proposed to simulate the mammalian cognitive system and to perform the neuroregulatory dynamics that play a critical role in the cognitive processes of the brain ...
Wei Sun   +3 more
doaj   +1 more source

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