Results 231 to 240 of about 70,807 (316)

A global effort toward standards for data sharing in biomedical imaging : Developing Consensus and Infrastructure for Global Data Interoperability. [PDF]

EMBO Rep
Winter SL, Moore J, Tavares AAS, Galloway G, Dojat M, Longo DL, Sullivan R, Mathur A, Chaabane L.   +8 more
europepmc   +1 more source

SEMEDA (Semantic Meta-Database) : ontology based semantic integration of biological databases

, 2003
Jacob Köhler
openalex   +1 more source

Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism

Advanced Science, EarlyView.
Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce, Aert F. Scheper, Aung Myat Phyo, Roisin O’ Flaherty, Richard Drake, Aiden Devitt, Martina Marchetti‐Deschmann, Radka Saldova, Abhay Pandit   +8 more
wiley   +1 more source

OntoTiger: a platform of ontology-based application tools for integrative biomedical exploration. [PDF]

Nucleic Acids Res
Yang H, He G, Zhang M, Fu H, He G, Wang C, Liu Y, Zhang S, Wang T, He YO, Cheng L.   +10 more
europepmc   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Strategies for community-sourced biocuration in bioinformatics: a case study on MIBiG 4.0. [PDF]

Brief Bioinform
Blin K, Loureiro C, Louwen NLL, Navarro-Muñoz JC, Gerstmans H, Robinson SL, Rutz A, Reitz ZL, Doering DT, van der Hooft JJJ, Weber T, Medema MH, Zdouc MM.   +12 more
europepmc   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Building a framework for reproducibility: the case for standardized data reporting and metadata integration in zebrafish research.

Dis Model Mech
Ngu MS, Toro S, Burger A, Ang KC.
europepmc   +1 more source

LLM-supported collaborative ontology design for data and knowledge management platforms. [PDF]

Front Big Data
Kampars J, Mosans G, Jogi T, Roters F, Vajragupta N.   +4 more
europepmc   +1 more source

The transhumanism of Ray Kurzweil. Is biological ontology reducible to computation?

, 2016
Javier Monserrat
openalex   +2 more sources