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Generalized Association Rules for Connecting Biological Ontologies
Bioinformatics, 2013The constantly increasing volume and complexity of available biological data requires new methods for managing and analyzing them. An important challenge is the integration of information from different sources in order to discover possible hidden ...
Fernando Benites, E. Sapozhnikova
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Molecular biological ontologies and ontological design patterns: what they are, and how they look
, 1999The amount of available information in molecular biology is vast, due to genome sequencing and gene expression chips. The structural, functional and evolutionary clues encoded in biological sequences have to be deciphered now. The combination of computer
J. Reich
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Jointly Integrating VCF-Based Variants and OWL-Based Biomedical Ontologies in MongoDB
IEEE/ACM Transactions on Computational Biology & Bioinformatics, 2020The development of the next-generation sequencing (NGS) technologies has led to massive amounts of VCF (Variant Call Format) files, which have been the standard formats developed with 1000 Genomes Project.
Jian Liu+5 more
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Integrating Biological and Engineering Ontologies
, 2013As methods for engineering data acquisition improve, methods for storing, generating knowledge from, and sharing that data for efficient reuse have become more important.
Jeffrey D. McPherson+5 more
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Ontologies: Formalising biological knowledge for bioinformatics.
Bioessays, 2003An ontology is a domain of knowledge structured through formal rules so that it can be interpreted and used by computers. Ontologies are becoming increasingly important in bioinformatics because they can be linked to the information in databases and ...
J. Bard
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Integrating Biological Pathways in Disease Ontologies
Medinfo, 2007Anatomy, clinical features, etiology, and morphology are the major organizing principles in existing disease ontologies. Assuming that biological pathways (including protein physical interactions, metabolic reactions, regulatory networks) will be in the ...
Julie Chabalier+2 more
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DEVELOPING ONTOLOGIES IN THE BIOLOGICAL DOMAIN
, 2007The development of q it has proven to be difficult for the biological community not only to develop but also to effectively use them. Why? How should they be developed in such a way that they are maintainable and usable by existing and novel information ...
A. G. Castro
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Using the hierarchy of biological ontologies to identify mechanisms in flat networks
Biology & Philosophy, 2017W. Bechtel
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Data Integration in the Life Sciences, 2009
B. Rance, J. Gibrat, C. Froidevaux
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B. Rance, J. Gibrat, C. Froidevaux
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