Results 111 to 120 of about 539,267 (342)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Tellurium, selenium and cobalt enrichment in Neoproterozoic black shales, Gwna Group, UK : Deep marine trace element enrichment during the Second Great Oxygenation Event [PDF]

, 2018
We are grateful to John Still for his skilled technical support and the ACEMAC facility at the University of Aberdeen. Research funded by NERC grant NE/M010953/1 and NERC facility grant IP-1631-0516. AJB is funded by NERC support of the Isotope Community
Armstrong, Joseph, Boyce, Adrian, Bullock, Liam A, Feldmann, Jörg, Parnell, John, Perez, Magali   +5 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of aeration on the removal of organic matter and nitrogen compounds in constructed wetlands treating the liquid fraction of piggery manure [PDF]

, 2019
The increasing demand for sustainable, robust and cost-efficient wastewater treatment techniques strengthen the implementation of constructed wetlands (CWs) in the agricultural sector.
Donoso Pantoja, Natalia Carolina, Kumar Biswas, Jayanta, Meers, Erik, Michels, Evi, van Oirschot, Dion   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Volatile fatty acids production from fermentation of secondary sewage sludge : a thesis presented in partial fulfillment of the requirements for the degree of Master of Engineering in Environmental Engineering [PDF]

, 2008
Sludge fermentation is used worldwide as an economical means to produce volatile fatty acids (VFA), which can be used as readily available carbon in biological nutrient removal (BNR) systems.
Banker, Sumit
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Impact of untreated tannery wastewater in the evolution of multidrug-resistant bacteria in Bangladesh

Scientific Reports
The tannery industry produces one of the worst contaminants, and unsafe disposal in nearby waterbodies and landfills has become an imminent threat to public health, especially when the resulting multidrug-resistant bacteria and heavy metals enter ...
Zimam Mahmud, Md Rasel Khan Manik, Adua Rahman, Muhammad Manjurul Karim, Laila N. Islam   +4 more
doaj   +1 more source

Evaluation of the potential of utilizing lactic acid bacteria and dairy wastewaters for methane production

Energy Exploration & Exploitation, 2017
The aim of this study was to assess the potential of utilizing Lactobacillus delbrüeckii spp. bulgaricus in order to improve the characteristics of dairy wastewater and produce biomethane. Nuclear magnetic resonance was utilized to assess the metabolites
Grazina Juodeikiene, Dalia Cizeikiene, Christoph Glasner, Elena Bartkiene, Alexander Dikiy, Elena Shumilina, Nebojša Ilić, Santino Di Berardino, César Foncesa   +8 more
doaj   +1 more source

A Terrestrial Single Chamber Microbial Fuel Cell-based Biosensor for Biochemical Oxygen Demand of Synthetic Rice Washed Wastewater

Sensors, 2016
Microbial fuel cells represent an innovative technology which allow simultaneous waste treatment, electricity production, and environmental monitoring.
Washington Logroño, Alex Guambo, Mario Pérez, Abudukeremu Kadier, Celso Recalde   +4 more
doaj   +1 more source