Results 81 to 90 of about 539,267 (342)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Influence of operating parameters on the biodegradation of steroid estrogens and nonylphenolic compounds during biological wastewater treatment processes [PDF]

, 2009
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Environmental Science & Technology, copyright © American Chemical Society after peer review.
Ahel M., Andersen H., Baronti C., Belfroid A. C., Birkett J. W., Burke M., Carballa M., Carballa M., Chiu T. Y., Clara M., Davenport R. J., D’Ascenzo G., Fürhacker M., Gaulk L. S., Giger W., Gomes R. L., Gomes R. L., Gomes R. L., Graham D. W., Holbrook R. D., Ifelebuegu A. O., Janex-Habibi M. L., Jobling S., Jobling S., Johnson A. C., Johnson A. C., Jones O. A. H., Joss A., Kirk L. A., Koh K., Koh Y. K. K., Koh Y. K. K., Koh Y. K. K., Kreuzinger N., Lagana A., Lai K. M., Lai K. M., Langford K., Langford K. H., Loyo-Rosales J. E., Nakada N., Obeng L. A., Onda K., Quinlivan P. A., Ren Y.-X., Renner R., Rosenfeldt E. J., Routledge E. J., Servos M. R., Snyder S. A., Stephenson T., Svenson A., Ternes T. A., Ternes T. A., Ternes T. A., Vader J. S.   +55 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Evaluation and characterization of selected pollutants in condition of surface water sources [PDF]

Acta Montanistica Slovaca, 2005
High quantities of organic matter can reduce the chemical and biological quality of river water. The key indicator of the oxygenation status of water bodies is the biological oxygen demand (BOD) and ammonium.
Martina Bendíková
doaj  

Electro-Fenton treatment process for brewery wastewater: effects of oxidant concentration and reaction time on BOD and COD removal efficiency

Journal of Engineering and Applied Science, 2022
The brewing process consumes and releases a large amount of wastewater into the environment. The objective of this study was to determine optimum operating conditions for the treatment of brewery wastewater using the Electro-Fenton (EF) process.
Oluwatosin A. Afolabi, Kenneth O. Adekalu, David A. Okunade   +2 more
doaj   +1 more source

Settling of bentonite in gelatine solutions [PDF]

, 2011
New Zealand has a sizeable meat by-products processing industry, associated with significant aqueous effluent called stickwater. Stickwater has a biological oxygen demand of 50-150 g O₂/l and has to be treated prior to disposal.
Lay, Mark C., Shamshudin, Rashid, Verbeek, Casparus Johan R.   +2 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Water pollution abatement by Chinese industry : cost estimates and policy implications [PDF]

Using factory-level data provided by China's National Environmental Protection Agency and the Tianjin Environmental Protection Bureau, the authors of this report estimate the costs of water pollution abatement for Chinese industry.
Chonghua Zhang, Dasgupta, Susmita, Huq, Minul, Wheeler, David   +3 more
core  

Utilization of the white-rot fungus, Trametes menziesii for landfill leachate treatment [PDF]

, 2015
The study monitored the characteristics of the leachate collected from ten different landfills and presented the experimental work for the treatment of leachate by immobilized Trametes menziesii.
Noor Zalina, M., Noorlidah Abdullah,, Wan Razarinah, W.A.R.   +2 more
core   +1 more source