Results 71 to 80 of about 635,426 (265)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Environmental parameters and biological datas
Environmental parameters and biological datas collected by State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin.
openaire +2 more sources
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The ultrasonic nonlinearity parameter for biological media
The nonlinearity parameter B/A of several soft tissues was measured using two independent methods. The B/A values of most soft tissues were found to be between 7 and 8, with the exception of fat which has a B/A value close to 11.
F. DUNN, W. K. LAW, L. A. FRIZZELL
doaj
Aspects of Biological Age Assessment and Its Significance in Ophthalmology
This article explores the key aspects of biological age assessment and the potential of studying this parameter in ophthalmology. Biological age, as an indicator of the state of the organism, differs from chronological age and allows for a more accurate ...
Yu. N. Yusef +2 more
doaj +1 more source
Background The neem tree, Azadirachta indica, is very promising for the control of many insect pests, where it acting as feeding deterrents, oviposition obstruction and as a growth regulator. Results In this study, both neem extract and neem nanoemulsion
Amany Ramadan Ebeid
doaj +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
On parameter interpretability of phenomenological-based semiphysical models in biology
Empirical and phenomenological-based models are used to represent biological and physiological processes. Phenomenological models are derived from the knowledge of the mechanisms that underlie the behavior of the system under study, while empirical ...
Laura Lema-Perez +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Pochazia shantungensis Chu & Lu, 1977 (Hemiptera: Ricaniidae) is an invasive insect species that poses a significant threat to agricultural crops and forest flora.
Gürsel Çetin +3 more
doaj +1 more source

