Results 1 to 10 of about 168 (168)
Computing topological parameters of biological networks [PDF]
Abstract Summary: Rapidly increasing amounts of molecular interaction data are being produced by various experimental techniques and computational prediction methods. In order to gain insight into the organization and structure of the resultant large complex networks formed by the interacting molecules, we have developed the versatile ...
Assenov, Y. +4 more
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Mapping parameter spaces of biological switches
Since the seminal 1961 paper of Monod and Jacob, mathematical models of biomolecular circuits have guided our understanding of cell regulation. Model-based exploration of the functional capabilities of any given circuit requires systematic mapping of multidimensional spaces of model parameters.
Rocky Diegmiller +7 more
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Analyzing biological network parameters with CentiScaPe [PDF]
Abstract Summary: The increasing availability of large network datasets along with the progresses in experimental high-throughput technologies have prompted the need for tools allowing easy integration of experimental data with data derived form network computational analysis. In order to enrich experimental data with network topological
Scardoni G +2 more
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Working Group on Biological Parameters (WGBIOP) [PDF]
The main objective of the Working Group on Biological Parameters (WGBIOP) is to review the status, issues, developments, and quality assurance of biological parameters for use in assessments and management that are in line with the requirements of end-users.
Godiksen, Jane Aanestad +38 more
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Setting Parameters for Biological Models With ANIMO [PDF]
ANIMO (Analysis of Networks with Interactive MOdeling) is a software for modeling biological networks, such as e.g. signaling, metabolic or gene networks. An ANIMO model is essentially the sum of a network topology and a number of interaction parameters.
Stefano Schivo +5 more
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Identification of parameter correlations for parameter estimation in dynamic biological models [PDF]
One of the challenging tasks in systems biology is parameter estimation in nonlinear dynamic models. A biological model usually contains a large number of correlated parameters leading to non-identifiability problems. Although many approaches have been developed to address both structural and practical non-identifiability problems, very few studies ...
Pu Li 0001, Quoc Dong Vu
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Biological passport parameters [PDF]
For long time anti-doping authorities have tried to find a way to tackle the use of forbidden substances and methods (namely erythropoiesis stimulating agents and blood transfusion) which improve sport performance through an increase of red cells and therefore oxygen transfer.
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Biological Parameters and the Acute LD50 Test
Abstract The acute LD50 is an inadequate index of toxicity because the catastrophe of death obscures the mechanisms and sites of action. Thus, nonlethal toxicity is not evaluated, and the LD50 is not extrapolated to the possible effects of low level exposures for long periods of time.
F, Sperling, J L, McLaughlin
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Chromatographic parameter determination for complex biological feedstocks [PDF]
The application of mechanistic models for chromatography requires accurate model parameters. Especially for complex feedstocks such as a clarified cell harvest, this can still be an obstacle limiting the use of mechanistic models. Another commonly encountered obstacle is a limited amount of sample material and time to determine all
Silvia M. Pirrung +6 more
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Telemetry System of Biological Parameters
The mobile telemetry system of biological parameters serves for reading and wireless data transfer of measured values of selected biological parameters to an outlying computer. It concerns basically long time monitoring of vital function of car pilot.The goal of this projects is to propose mobile telemetry system for reading, wireless transfer and ...
Spišák, J., Penhaker, M.
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