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What Are Biologics, Biological Products and Biological Drugs?
2014Following the deaths of 14 children from contaminated antitoxins and smallpox vaccines, Congress in 1902 passed the Biologics Control Act, which is also known as The Virus-Toxin Law. This act required manufacturers to be licensed for safety and was a precursor and model for the Food Drugs and Cosmetics Act of 1938 which also emphasized safety.
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The Biological Productivity of Waters
Journal of the Fisheries Research Board of Canada, 1966[The concept of biological production is best approached from the point of view of a product, defined as a group of organisms (not necessarily all belonging to the same species) which have similar food habits, and which are useful to man or are of special interest for some other reason.
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The Gastrins: Their Production and Biological Activities
Annual Review of Physiology, 2001▪ Abstract Gastric epithelial organization and function are controlled and maintained by a variety of endocrine and paracrine mediators. Peptides encoded by the gastrin gene are an important part of this system because targeted deletion of the gene, or of the gastrin-CCKB receptor gene, leads to decreased numbers of parietal cells and decreased ...
Rod Dimaline +3 more
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The Biological Production of Angiotensin
1974The reaction of kidney renin with its plasma substrate to form angiotensin has been studied for many years using both crude and purified materials derived from many species. Much effort has been expended in the attempt to show the existence or efficacy of inhibitors or activators of the reaction.
Joseph R. Kahn +4 more
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Sustained Biological Productivity
1972When the organizers of this Conference asked me to contribute a paper on sustained biological productivity, I presumed they had in mind the International Biological Programme (IBP) which runs for the decade of 1964–74, with more than sixty countries participating.
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An adapted F‐test for homogeneity of variability in follow‐on biological products
Statistics in Medicine, 2013In recent years, follow‐on biological products (biosimilars) have received much attention from both the biotechnology industry and the regulatory agencies, especially after the passage of the 2010 healthcare reform bill.
Jun Yang, N. Zhang, S. Chow, Eric M. Chi
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Cholesterol oxidation products and their biological importance
Chemistry and Physics of Lipids, 2016The main biological cause of oxysterols is the oxidation of cholesterol. They differ from cholesterol by the presence of additional polar groups that are typically hydroxyl, keto, hydroperoxy, epoxy, or carboxyl moieties. Under typical conditions, oxysterol concentration is maintained at a very low and precisely regulated level, with an excess of ...
Waldemar Kulig +5 more
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Risk Management for Biological Products
International Journal of Pharmaceutical Medicine, 2004The risks of biotechnology-derived products and other biologicals are different from the risks of small chemical entities and, thus, their risk management will have special features. For many biological products, the safety is mainly dependent on the starting materials and the manufacturing process.
Outi Nieminen, Pekka Kurki
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, 2012
Over the past few decades, Asian aquaculture production has intensified rapidly through the adoption of technological advances, and the use of a wide array of chemical and biological products to control sediment and water quality and to treat and prevent
A. Rico +6 more
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Over the past few decades, Asian aquaculture production has intensified rapidly through the adoption of technological advances, and the use of a wide array of chemical and biological products to control sediment and water quality and to treat and prevent
A. Rico +6 more
semanticscholar +1 more source
Osmoregulation and Biological Energy Production
1980The interests of the Department of Energy (DOE) in osmoregulation research are fairly straightforward. As you are all aware, there is much being made these days about the importance of biomass and how biomass can serve as an alternate to fossil fuels. Many of these claims are highly optimistic while others tend to minimize the contribution that biomass
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