Results 161 to 170 of about 84,360 (250)

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

open access: yesSmall, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa   +18 more
wiley   +1 more source

A Label‐Free Ultraviolet Photoacoustic Microscopy Enables Nuclear Imaging and Toxicity Assessment in an Intact Brain Organoid

open access: yesSmall, EarlyView.
Ultraviolet photoacoustic microscopy enables label‐free visualization of nuclear morphology in intact human brain organoids. By exploiting endogenous nucleic acid absorption at 266 nm, this approach resolves individual nuclei without staining or sectioning.
Hyunjun Kye   +5 more
wiley   +1 more source

Aerobic Microbiological Profile and Antimicrobial Resistance Trends in Sterile Body Fluid Infections Over Nine Years: A Retrospective Analysis from a Tertiary-Care Center. [PDF]

open access: yesInfect Drug Resist
Alharbi NA   +12 more
europepmc   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei   +6 more
wiley   +1 more source

Ecotoxicological Assessment of Mercury in Fish From a Gold‐Mining‐Impacted Amazonian River: Biomonitoring and Human Health Risk

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The Peixoto de Azevedo River, located in northern Mato Grosso, southern Brazilian Amazon, has a long history of artisanal and small‐scale gold mining (ASGM). This study evaluated total mercury (THg) concentrations in fish tissues to assess biomagnification and potential risks.
Augusto Cesar da Costa Castilho   +5 more
wiley   +1 more source

ANGPT2 Drives Thyroid Cancer Progression Through PI3K/AKT Signaling and Correlates With Poor Prognosis and Immune Infiltration

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen   +5 more
wiley   +1 more source

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