Results 1 to 10 of about 795,490 (279)

Cryo-plasma FIB/SEM volume imaging of biological specimens [PDF]

eLife, 2023
Serial focussed ion beam scanning electron microscopy (FIB/SEM) enables imaging and assessment of subcellular structures on the mesoscale (10 nm to 10 µm). When applied to vitrified samples, serial FIB/SEM is also a means to target specific structures in
Maud Dumoux, Thomas Glen, Jake LR Smith, Elaine ML Ho, Luis MA Perdigão, Avery Pennington, Sven Klumpe, Neville BY Yee, David Andrew Farmer, Pui YA Lai, William Bowles, Ron Kelley, Jürgen M Plitzko, Liang Wu, Mark Basham, Daniel K Clare, C Alistair Siebert, Michele C Darrow, James H Naismith, Michael Grange   +19 more
doaj   +2 more sources

Detection of Glycosaminoglycans in Biological Specimens. [PDF]

Methods Mol Biol, 2023
Proteoglycans (PGs) are macromolecules formed by a protein backbone to which one or more glycosaminoglycan (GAG) side chains are covalently attached. Most PGs are present in connective tissues, cell surfaces, and intracellular compartments. The major biological function of PGs derives from the GAG component of the molecule, which is involved in cell ...
Khan SA, Nidhi FNU, Amendum PC, Tomatsu S.   +3 more
europepmc   +3 more sources

Critical Factors in Sample Collection and Preparation for Clinical Metabolomics of Underexplored Biological Specimens [PDF]

Metabolites
This review article compiles critical pre-analytical factors for sample collection and extraction of eight uncommon or underexplored biological specimens (human breast milk, ocular fluids, sebum, seminal plasma, sweat, hair, saliva, and cerebrospinal ...
Hygor M. R. de Souza, Tássia T. P. Pereira, Hanna C. de Sá, Marina A. Alves, Rafael Garrett, Gisele A. B. Canuto   +5 more
doaj   +2 more sources

SpeciMate: Improving metadata extraction from digitised biological specimens [PDF]

Biodiversity Data Journal
The digitisation of natural history collections represents a critical step towards preserving and increasing accessibility to valuable scientific data.
Alan Stenhouse, Peter Thrall
doaj   +4 more sources

Determination of aluminum concentrations in biological specimens: application in the clinical laboratory [PDF]

Advances in Laboratory Medicine, 2022
Aluminum enters the body primarily through diet or occupational exposure, and is cleared through urine. However, this trace element may accumulate and cause toxicity in subjects with renal insufficiency, and even in dialysis patients.
San Martín Sonia Pérez, Bauçà Josep Miquel, Martinez-Morillo Eduardo   +2 more
doaj   +2 more sources

Application of a universal parasite diagnostic test to biological specimens collected from animals [PDF]

International Journal for Parasitology: Parasites and Wildlife, 2023
A previously described universal parasite diagnostic (nUPDx) based on PCR amplification of the 18S rDNA and deep-amplicon sequencing, can detect human blood parasites with a sensitivity comparable to real-time PCR. To date, the efficacy of this assay has
Meredith Lane, Mitra Kashani, Joel LN. Barratt, Yvonne Qvarnstrom, Michael J. Yabsley, Kayla B. Garrett, Richard S. Bradbury   +6 more
doaj   +2 more sources

Collection and disinfection of forensic biological specimens in five cases concerning COVID-19 in Guangzhou, China [PDF]

Forensic Science International: Synergy, 2020
There have been many cases of pneumonia caused by novel coronavirus infections in China and around the world. This will inevitably lead to a rise in the number of patients.
Xingyi Yang, Quyi Xu, Hong Liu, Jichao Xu, Dian Yang, Cheng xiao, Huiying Hu, Yunyun Liu, Chao Liu   +8 more
doaj   +2 more sources

Determination of Arylcyclohexylamines in Biological Specimens: Sensors and Sample Pre-Treatment Approaches [PDF]

Micromachines
Arylcyclohexylamine (ACH) compounds represent a predominant faction within new psychoactive substances. Due to their powerful dissociative effects, they are used in recreational contexts but also in situations of drug-facilitated sexual assault, and ...
Rodrigo Pelixo, Mário Barroso, Eugenia Gallardo, Tiago Rosado   +3 more
doaj   +2 more sources

Low-dose phase retrieval of biological specimens using cryo-electron ptychography [PDF]

Nature Communications, 2020
Cryo-electron microscopy is widely employed in structural biology and uses phase contrast imaging. Here, the authors employ electron ptychography, a quantitative phase retrieval method for high-contrast, low-dose phase imaging of cryo-state rotavirus and
Liqi Zhou, Jingdong Song, Judy S. Kim, Xudong Pei, Chen Huang, Mark Boyce, Luiza Mendonça, Daniel Clare, Alistair Siebert, Christopher S. Allen, Emanuela Liberti, David Stuart, Xiaoqing Pan, Peter D. Nellist, Peijun Zhang, Angus I. Kirkland, Peng Wang   +16 more
doaj   +2 more sources

Easy ultrastructural insight into the internal morphology of biological specimens by Atomic Force Microscopy [PDF]

Scientific Reports, 2021
As a topographical technique, Atomic Force Microscopy (AFM) needs to establish direct interactions between a given sample and the measurement probe in order to create imaging information.
Fabian Christopher Herrmann
doaj   +2 more sources