Results 61 to 70 of about 795,490 (279)

THREE-DIMENSIONAL OBSERVATIONS ON THICK BIOLOGICAL SPECIMENS BY HIGH VOLTAGE ELECTRON MICROSCOPY

Image Analysis and Stereology, 2011
Thick biological specimens prepared as whole mount cultured cells or thick sections from embedded tissues were stained with histochemical reactions, such as thiamine pyrophosphatase, glucose-6-phosphatase, cytochrome oxidase, acid phosphatase, DAB ...
Tetsuji Nagata
doaj   +1 more source

Biological applications of the NanoSuit for electron imaging and X-microanalysis of insulating specimens

Applied Microscopy, 2022
Field emission scanning electron microscopy (FESEM) is an essential tool for observing surface details of specimens in a high vacuum. A series of specimen procedures precludes the observations of living organisms, resulting in artifacts.
Ki Woo Kim
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Nanotechnology in bioanalysis: Current trends and applications

Journal of Chromatography Open
Nanotechnology has evolved into an interdisciplinary trend spanning nearly all scientific domains and has had a profound impact on the global community over the last decade.
Arshdeep Chopra, Yogindra Kumari, Samarth Kumar, Renuka Sharma, Rohit Bhatia   +4 more
doaj   +1 more source

Elemental microanalysis of biological specimens.

Scanning microscopy, 1988
Although X-ray microanalysis in the electron microscope is the most common method for microanalysis of biological specimens, other methods of elemental microanalysis (electron energy loss spectroscopy, scanning Auger microanalysis, and proton, ion, and laser microprobe analysis) may provide important complementary information and help overcome some of ...
Roomans, Godfried M., Wroblewski, Joanna, Wróblewski, Romuald   +2 more
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

In Vitro Corrosion and Biological Assessment of Bioabsorbable WE43 Mg Alloy Specimens

Journal of Manufacturing and Materials Processing, 2017
Bioabsorbable magnesium (Mg) alloys have several advantages in biomedical implant applications as they reduce certain risks associated with conventional permanent implants.
Emmet Galvin, Swarna Jaiswal, Caitríona Lally, Bryan MacDonald, Brendan Duffy   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

First occurrence of the non-native bryozoan Schizoporella japonica Ortmann (1890) in Western Europe [PDF]

, 2014
Schizoporella japonica Ortmann was described from Japan but was subsequently introduced on Pacific oysters to the Pacific coast of North America, where it is now well established. In this paper we record it for the first time in European waters.
Holt, Rohan, JS, Ryland, Loxton, Jennifer, Porter, Joanne, Spencer Jones, Mary   +4 more
core   +1 more source