Results 81 to 90 of about 795,490 (279)

The impact of one-decade ecological disturbance on genetic changes : a study on the brine shrimp Artemia urmiana from Urmia Lake, Iran [PDF]

, 2019
Urmia Lake, the largest natural habitat of the brine shrimp Artemia urmiana, has progressively desiccated over the last two decades, resulting in a loss of 80% of its surface area and producing thousands of hectares of arid salty land.
Asem, Alireza, Eimanifar, Amin, Sun, Shi-Chun, Van Stappen, Gilbert   +3 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Revisiting the Andean butterfly Eryphanis zolvizora group (Lepidoptera, Nymphalidae) : one or several species? [PDF]

, 2014
Eryphanis zolvizora (Hewitson, 1877) is a rare Andean endemic butterfly, described from Bolivia, which has been historically classified either as a unique species, or as part of a group of three allopatric species from Bolivia, Ecuador and Colombia.
Blandini, Patrick, Bristow, Roger, Gareca, Yuvinka, Huertas, Blanca, Neild, Andrew, Sousa, Juan Carlos de   +5 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Effects of Various Metallic Surfaces on Cellular and Bacterial Adhesion

Metals, 2019
The effects of Ti, Nb, Ta, Zr, and Ag on cellular and bacterial adhesion were investigated in this study. Moreover, the relationships between surface compositions, metal ion release behaviors, and biological responses were examined. As a result, MC3T3-E1
Masaya Shimabukuro, Haruka Ito, Yusuke Tsutsumi, Kosuke Nozaki, Peng Chen, Risa Yamada, Maki Ashida, Akiko Nagai, Takao Hanawa   +8 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Use of shuttle for life sciences [PDF]

The use of the space shuttle in carrying out biological and medical research programs, with emphasis on the sortie module, is examined. Detailed descriptions are given of the goals of space life science disciplines, how the sortie can meet these goals ...
Mcgaughy, R. E.
core   +1 more source

Moths of the Douglas Lake Region (Emmet and Cheboygan Counties), MIchigan: I. Sphingidae - Ctenuchidae (Lepidoptera) [PDF]

, 2017
Excerpt: For more than 60 years, workers at the University of Michigan Biological Station have been concerned with the flora and fauna of the Douglas Lake Region - now generally defined, for ease of boundaries.
Voss, Edward G.
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

PERSIAN cohort biobank: creating a large-scale national resource for biomedical research in Iran

BMC Public Health
Background Biobanks are essential for advancing biomedical research by providing access to high-quality biological specimens and associated data. In the Middle East, large-scale biorepositories are limited, hindering regional epidemiological and genetic ...
Amaneh Shayanrad, SeyedehFatemeh Mousavi, Sara Eftekhari, Gholamreza Roshandel, Rana Irilouzadian, Hossein Poustchi, Reza Malekzadeh   +6 more
doaj   +1 more source