Microbiological quality and genotoxicity of domestic water sources: A combined approach using Micro Biological Survey method and mutagenesis assay (micronucleus test) in root tips of Vicia faba in the West region of Cameroon. [PDF]
PLoS One, 2021 Mabvouna RB +6 more
europepmc +1 more source
A Survey of Isatin Hybrids and their Biological Properties
Molecular DiversityThe emergence of diverse infections worldwide, which is a serious global threat to human existence, necessitate the urgent development of novel therapeutic candidates that can combat these diseases with efficacy. Isatin, a secondary metabolite from tryptophan is considered a privileged scaffold and favorable pharmacophore with a unique structural ...
Shu, Vanessa Asoh +2 more
openaire +2 more sources
Treehoppers (Hemiptera: Aetalionidae and Membracidae) from Madre de Dios region, Peru [PDF]
, 2019 A list of treehoppers (Aetalionidae and Membracidae) is presented from Madre de Dios region at the southeastern Amazon basin in Peru. The treehopper specimens were collected as by-catch in a survey of the beetles in the Villa Carmen Biological Station ...
Chaboo, Caroline S. +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 1939 An article detailing further developments in the bathymetric survey work as detailed in the 6th annual report of the Freshwater Biological Association.
Mortimer, C.H.
core
Molecular Biology at the Quantum Level: Can Modern Density Functional Theory Forge the Path?
, 2012 Recent years have seen vast improvements in the ability of rigorous quantum-mechanical methods to treat systems of interest to molecular biology. In this review article, we survey common computational methods used to study such large, weakly bound ...
Kolb, Brian, Thonhauser, T.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
PREDICTED FUTURE ECONOMIC IMPACTS OF BIOLOGICAL CONTROL OF LEAFY SPURGE IN THE UPPER MIDWEST [PDF]
The Leafy Spurge Biological Control program was designed to use insects and plant diseases from the plant's original European habitat to control infestations in the United States.
Bangsund, Dean A. +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source