Results 121 to 130 of about 30,599,032 (364)

Methods of determining the quality of water using the functional characteristics of algae [PDF]

open access: yes, 1980
In the study of questions relating to the quality of raw water and the biological produc- tivity of water bodies algal indicators have an important place.
Sirenko, L.A.
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Organoids pharmacology and toxicology

open access: yesEngMedicine
Model evolution is crucial for understanding the effects and safety of drugs in pharmacological and toxicological research. Traditional cell lines and animal models have contributed significantly to drug development.
Jie Sun   +7 more
doaj   +1 more source

Dynamics of Spatial Exploitation: A Metapopulation Approach [PDF]

open access: yes
We present a bioeconomic model of a harvesting industry operating over a heterogeneous environment comprised of discrete biological populations interconnected by dispersal processes. The model generalizes the H. S. Gordon [1954]/V.
Sanchirico, James, Wilen, James
core  

Therapeutic target discovery using Boolean network attractors: improvements of kali

open access: yes, 2018
In a previous article, an algorithm for identifying therapeutic targets in Boolean networks modeling pathological mechanisms was introduced. In the present article, the improvements made on this algorithm, named kali, are described.
Guziolowski, Carito, Poret, Arnaud
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Ancient and methane-derived carbon subsidizes contemporary food webs

open access: yesNature Communications, 2016
Alluvial aquifers of river floodplains support abundant large-bodied consumers despite an absence of light and scarcity of organic carbon. DelVecchia et al.
Amanda G. DelVecchia   +2 more
doaj   +1 more source

Effect of Biological Contact Filters (BCFs) on Membrane Fouling in Drinking Water Treatment Systems [PDF]

open access: gold, 2017
Sunao Hasegawa   +6 more
openalex   +1 more source

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