Results 181 to 190 of about 29,478,974 (394)

OXIDATION-REDUCTION SYSTEMS OF BIOLOGICAL SIGNIFICANCE

open access: hybrid, 1929
Leonor Michaelis, E. S. Guzmán Barrón
openalex   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Soil as a biological system

open access: yes, 2002
Soil plays a fundamental and irreplaceable role in the biosphere because it governs plant productivity of terrestrial ecosystem, allows the completion of the biogeochemical cycles and microorganisms inhabiting soil degrade, sooner or later, all organic compounds including those more recalcitrant.
PIETRAMELLARA, GIACOMO   +3 more
openaire   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Organoids pharmacology and toxicology

open access: yesEngMedicine
Model evolution is crucial for understanding the effects and safety of drugs in pharmacological and toxicological research. Traditional cell lines and animal models have contributed significantly to drug development.
Jie Sun   +7 more
doaj  

Preliminary analysis of a radiobiological experiment for LifeSat [PDF]

open access: yes
With the possibility of performing radiation life science experiments on a dedicated satellite (LifeSat) in space, a combined effort in radiation physics and radiation dosimetry, in addition to radiation biology, is clearly required to ensure that ...
Atwell, William   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy