Results 151 to 160 of about 3,876,466 (316)

Annual Report - Marine Biological Laboratory, 1888

, 1889
Annual report of the Marine Biological Laboratory in Woods Hole. 1888.
Marine Biological Laboratory (Woods Hole MA)
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Optimization of Diffusion MRI With Consideration of the Signal Decay in Biological Tissues. [PDF]

Magn Reson Med
Kuczera S, Maier SE.
europepmc   +1 more source

Hydrogel composite mimics biological tissues. [PDF]

Soft Matter, 2022
Horkay F, Basser PJ.
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1892

, 1892
Annual report of the Marine Biological Laboratory in Woods Hole. 1892.
Marine Biological Laboratory (Woods Hole MA)
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Nanoscale Imaging of Biological Tissues: Techniques, Challenges and Emerging Frontiers. [PDF]

Nanomaterials (Basel)
Kajla R, Leija-Cardenas R, Shivalingaiah MM, Shabbir MW, Ou Z.   +4 more
europepmc   +1 more source

Distinct thermal effect on biological tissues using subwavelength ultrasound metalens at megahertz. [PDF]

iScience, 2023
Zheng Y, Li C, Zhang C, He J, Jiang X, Ta D.   +5 more
europepmc   +1 more source

Annual Report - Marine Biological Laboratory, 1957

, 1957
Annual report of the Marine Biological Laboratory in Woods Hole. 1957.
Marine Biological Laboratory (Woods Hole MA)
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source