Results 201 to 210 of about 6,267,247 (357)

Biological transport processes and space dimension.

Proceedings of the National Academy of Sciences of the United States of America, 1991
W. Nadler, D. Stein
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Transport of the uremic toxin symmetric dimethylarginine (SDMA) by renal transport proteins. [PDF]

Amino Acids
Scherpinski LA, Fromm MF, Maas R, König J.   +3 more
europepmc   +1 more source

Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers — an in-vitro model of intestinal transport [PDF]

, 2008
Vamsi Madgula, Bharathi Avula, Young Whan Choi, Srinivas V. Pullela, Ikhlas A. Khan, Larry Walker, Shabana I. Khan   +6 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Holographic nature of critical quantum states of proteins. [PDF]

Comput Struct Biotechnol J
Papp E, Vattay G.
europepmc   +1 more source

Formulation of a coupled mechanism between solute diffusion, phosphatase–kinase reactions and membrane potentials for the primary active transport of phosphorylated substrates through biological membranes

, 2002
Bernard Maı̈sterrena, Koffi Fiaty, Catherine Charcosset, B. Perrin, Roger Couturier, Ian C. West   +5 more
openalex   +1 more source

Comparative molecular biological analysis of membrane transport genes in organisms [PDF]

, 2008
Toshifumi Nagata, Shigemi Iizumi, Kouji Satoh, Shoshi Kikuchi   +3 more
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Functional transposition of renal functions to the posterior intestine during maturation in male three-spined stickleback. [PDF]

Sci Rep
Bezabhe YH, Paylar B, Seyoum A, Borg B, Olsson PE.   +4 more
europepmc   +1 more source