Results 41 to 50 of about 27,101 (296)

Sperm Cell Driven Microrobots—Emerging Opportunities and Challenges for Biologically Inspired Robotic Design

Micromachines, 2020
With the advent of small-scale robotics, several exciting new applications like Targeted Drug Delivery, single cell manipulation and so forth, are being discussed.
Ajay Vikram Singh, Mohammad Hasan Dad Ansari, Mihir Mahajan, Shubhangi Srivastava, Shubham Kashyap, Prajjwal Dwivedi, Vaibhav Pandit, Uma Katha   +7 more
doaj   +1 more source

Validation of Biologically Inspired Tactics to Increase Multi-Agent System Resilience

IEEE Open Journal of Systems Engineering, 2023
There is an urgent need to increase multi-agent systems’ resilience. Efforts, however, are hampered by three gaps: current approaches are case study specific, may depend on infrastructure investment, and are often unshared.
Bryan C. Watson, Isabella V. Hernandez, Marc J. Weissburg, Bert Bras   +3 more
doaj   +1 more source

Biologically Inspired Design: A Primer:Synthesis Lectures on Engineering, Science, and Technology

, 2021
As the existence of all life forms on our planet is currently in grave danger from the climate emergency caused by Homo sapiens, the words "sustainability" and "eco-responsibility" have entered the daily-use vocabularies of scientists, engineers ...
Lenau, Torben A., Lakhtakia, Akhlesh
core   +1 more source

Engineering a heparin-mimetic biomaterial to promote tissue vascularization

Communications Biology
A major challenge in tissue engineering involves the development of synthetic biomaterials that effectively induce and maintain functional vascularization of engineered tissue constructs post implantation.
Linqing Li, Jinling Yang, Luba Perry, Jennifer L. Bays, Sangeeta N. Bhatia, Jeroen Eyckmans, Christopher S. Chen   +6 more
doaj   +1 more source

The Advanced BioTRIZ Method Based on LTE and MPV

Biomimetics
While BioTRIZ is widely employed in biomimetic design to facilitate creative ideation and standardize workflows, accurately formulating domain conflicts and assessing design schemes during critical stages—such as initial concept development and scheme ...
Zhonghang Bai, Linyang Li, Yufan Hao, Xinxin Zhang   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Developing pervasive multiagent systems with nature-inspired co-ordination [PDF]

, 2015
Pervasive computing systems can be modelled effectively as populations of interacting autonomous components. The key challenge to realizing such models is in getting separately-specified and -developed sub-systems to discover and interoperate with each ...
Rosi, Alberto, Stevenson, Graeme, di Marzo Serugendo, Giovanan, Fernandez Marquez, Jose-Luis, Juan Ye, Fernandez Marquez, Jose Luis, De Angelis, Francesco L., Franco Zambonelli, Omicini, Andrea, Castelli, Gabriella, Anzengruber, Bernhard, Ferscha, Alois, Simon Dobson, Gabriella Castelli, Dobson, Simon, Molesini, Ambra, Serugendo, Giovanna Di Marzo, Stevenson, Graeme Turnbull, Viroli, Mirko, Zambonelli, Franco, DeAngelis, Francesco, Ye, Juan, Nieminen, Jussi, Marco Mamei, Graeme Stevenson, Alois Ferscha, Matteo Risoldi, Montagna, Sara, Mariani, Stefano, Giovanna Di Marzo Serugendo, Pianini, Danilo, Alberto Rosi, Dobson, Simon Andrew, Bernhard Anzengruber, Francesco L. DeAngelis, Mamei, Marco, Jose Luis Fernandez Marquez, Jussi Nieminen, Risoldi, Matteo   +38 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Innovative and Biologically Inspired PETRA IV Girder Design [PDF]

, 2021
DESY (Deutsches Elektronen Synchrotron) is currently expanding the PETRA III storage ring X-ray radiation source to a high-resolution 3D X-ray microscope providing all length scales from the atom to millimeters.
Meyners, Norbert, Thoden, Daniel, Andresen, Simone   +2 more
core   +1 more source