Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Identification of the novel c.149-8C>G splicing variant in RHCE*02 that weakens C antigen expression. [PDF]
Tournamille C +6 more
europepmc +1 more source
Mitochondrial physiology in cardiac muscle of deer mice native to high altitude
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem +3 more
wiley +1 more source
Toward fully algorithmic care for type 1 diabetes: The case for AI autonomy, and a recalibrated role for the diabetologist in an ageing type 2 diabetes population. [PDF]
Maaz M +5 more
europepmc +1 more source
Despite having similar climatic niches, woody plant species can exhibit contrasting responses to climate change. Using MaxEnt and spatial prioritization, we evaluated Isoberlinia doka and I. tomentosa under future climate scenarios (2041–2060). Despite high niche overlap (D = 0.635; I = 0.788), I. doka experienced severe habitat contraction, whereas I.
Sessi Gilles Christian Adjahossou +8 more
wiley +1 more source
First Fatal Case of Adult Meningoencephalitis Caused by Pasteurella canis: An Autopsy Case Report. [PDF]
Pefferkorn E +5 more
europepmc +1 more source
ABSTRACT Stomach cancer (SC) or gastric cancer (GC) is one of the most common gastrointestinal malignancies. Currently, some studies based on competing endogenous RNAs (ceRNA) network analysis have been assessed for this cancer. The construction and analysis of ceRNA network is a novel approach for identification of RNA‐based biomarkers in cancer ...
Habib MotieGhader +2 more
wiley +1 more source
Evaluating the Potential Infectious Risk Profile of Biologics in Chronic Rhinosinusitis With Nasal Polyposis. [PDF]
Fieux M, Gevaert P, Sowerby LJ.
europepmc +1 more source
Performances and Fatigue Responses to Weighted Vest Training in Parkour Novices
ABSTRACT Weighted vest training has demonstrated benefits for muscle strength, which is critical for parkour performance. However, the acute effects of external loading in this discipline remain poorly understood. This study investigated the impact of weighted vest use during parkour sessions on lower‐limb performance, perceived exertion, and muscle ...
Sidney Grosprêtre +5 more
wiley +1 more source

