Radiotelemetry Of Heart Rates From Free-Ranging Gulls [PDF]
A lightweight radiotelemetry system with a range of 80 km was used to monitor heart rate from free-ranging Herring Gulls on flights of up to 20 km. Heart rate varied from 130 beats/min in a resting bird to 625 beats/min for sustained flight.
Kanwisher, J. W. +3 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Interaction Between The MEC1-Dependent DNA Synthesis Checkpoint And G1 Cyclin Function In Saccharomyces Cerevisiae [PDF]
The completion of DNA synthesis in yeast is monitored by a checkpoint that requires MEC1 and RAD53. Here we show that deletion of the Saccharomyces cerevisiae G1 cyclins CLN1 and CLN2 suppressed the essential requirement for MEC1 function.
Cross, F. R., Vallen, Elizabeth Ann
core +1 more source
Why emerging leaders should focus on being good postdoctoral supervisors
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski +5 more
wiley +1 more source
Chemical Biology & Drug Design: Special Thematic Issues on a Molecular Armamentarium of Novel Chemical and Biological Medicines for the War on Disease and Innovative Technologies Enabling the Life Sciences and Drug Discovery [PDF]
Tomi K. Sawyer
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
An Inquiry-Infused Introductory Biology Laboratory That Integrates Mendel\u27s Pea Phenotypes With Molecular Mechanisms [PDF]
We developed a multi-week laboratory in which college-level introductory biology students investigate Mendel\u27s stem length phenotype in peas. Students collect, analyze and interpret convergent evidence from molecular and physiological techniques.
Kaplinsky, Nicholas J. +2 more
core +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Matrix Adhesion Polarizes Heart Progenitor Induction In The Invertebrate Chordate Ciona Intestinalis [PDF]
Cell-matrix adhesion strongly influences developmental signaling. Resulting impacts on cell migration and tissue morphogenesis are well characterized. However, the in vivo impact of adhesion on fate induction remains ambiguous.
Cooley, J. +4 more
core +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source

