Results 111 to 120 of about 9,228,169 (408)
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Each of us has felt afraid, and we can all recognize fear in many animal species. Yet there is no consensus in the scientific study of fear. Some argue that 'fear' is a psychological construct rather than something discoverable through scientific investigation.
openaire +5 more sources
Radar And Visual Observations Of Autumnal (Southward) Shorebird Migration On Guam [PDF]
Several species of shorebirds migrate between eastern Asia and the southern Pacific islands, Australia, and New Zealand. Observations made from Guam (13°25′N, 144°45′E) during autumn 1983 indicate that a significant number of birds take a direct route ...
Williams, J. M.+1 more
core +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
Correction: a bioenergetic basis for membrane divergence in archaea and bacteria. [PDF]
PLOS Biology Staff
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Multiple Signaling Functions Of Song In A Polymorphic Species With Alternative Reproductive Strategies [PDF]
Vocal traits can be sexually selected to reflect male quality, but may also evolve to serve additional signaling functions. We used a long-term dataset to examine the signaling potential of song in dimorphic white-throated sparrows (Zonotrichia ...
Formica, Vincent A.+4 more
core +2 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Actuarial Senescence In A Dimorphic Bird: Different Rates Of Ageing In Morphs With Discrete Reproductive Strategies [PDF]
It is often hypothesized that intra-sexual competition accelerates actuarial senescence, or the increase in mortality rates with age. However, an alternative hypothesis is that parental investment is more important to determining senescence rates.
Barcelo-Serra, M.+7 more
core +1 more source