Results 191 to 200 of about 8,754,748 (363)
Correction: Bacterial gene 5' ends have unusual mutation rates that can mislead tests of selection. [PDF]
PLOS Biology Staff.
europepmc +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Comment on Korkmaz et al. A Deep Learning and Explainable AI-Based Approach for the Classification of Discomycetes Species. <i>Biology</i> 2025, <i>14</i>, 719. [PDF]
Pastore EP.
europepmc +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Correction: Dynamic grouping of hippocampal neural activity during cognitive control of two spatial frames. [PDF]
PLOS Biology Staff
doaj +1 more source
Vessels in Middle-Earth: meeting report from the 2025 Australasian Summit on Vascular Biology and Microcirculation. [PDF]
Okuda KS +3 more
europepmc +1 more source
Charting a new vision: lessons on Vision & Change from a network of biology educators
Jeremy Hsu +7 more
openalex +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source

