Results 201 to 210 of about 3,613,281 (296)
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Using anti-DEI policies to dismantle education: A new front in a really old battle. [PDF]
Ballen CJ, McGlynn T, Zamudio KR.
europepmc +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
The biology of dragonflies : (Odonata or Paraneuroptera) / by R.J. Tillyard.
R. J. Tillyard
openalex +4 more sources
Author Correction: A thermosensor FUST1 primes heat-induced stress granule formation via biomolecular condensation in Arabidopsis. [PDF]
Geng P+14 more
europepmc +1 more source
Animal biology : an elementary text-book /
C. Lloyd Morgan, James Greig Smith
openalex +2 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source