Results 71 to 80 of about 9,228,169 (408)

Astrocytes: biology and pathology

open access: yesActa Neuropathologica, 2009
Astrocytes are specialized glial cells that outnumber neurons by over fivefold. They contiguously tile the entire central nervous system (CNS) and exert many essential complex functions in the healthy CNS.
M. Sofroniew, H. Vinters
semanticscholar   +1 more source

The Embryonic Transcriptome Of The Red-Eared Slider Turtle (Trachemys Scripta) [PDF]

open access: yes, 2013
The bony shell of the turtle is an evolutionary novelty not found in any other group of animals, however, research into its formation has suggested that it has evolved through modification of conserved developmental mechanisms.
Cebra-Thomas, J.   +14 more
core   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Biopython: freely available Python tools for computational molecular biology and bioinformatics

open access: yesBioinform., 2009
Summary: The Biopython project is a mature open source international collaboration of volunteer developers, providing Python libraries for a wide range of bioinformatics problems. Biopython includes modules for reading and writing different sequence file
P. Cock   +10 more
semanticscholar   +1 more source

Correction: How Many Parameters Does It Take to Describe Disease Tolerance? [PDF]

open access: yesPLoS Biology, 2016
[This corrects the article DOI: 10.1371/journal.pbio.1002435.].
PLOS Biology Staff
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Human organoids: model systems for human biology and medicine

open access: yesNature reviews. Molecular cell biology, 2020
The historical reliance of biological research on the use of animal models has sometimes made it challenging to address questions that are specific to the understanding of human biology and disease. But with the advent of human organoids — which are stem
Jihoon Kim, B. Koo, J. Knoblich
semanticscholar   +1 more source

Correction: The Sacred Ibis debate: The first test of evolution. [PDF]

open access: yesPLoS Biology, 2018
[This corrects the article DOI: 10.1371/journal.pbio.2005558.].
PLOS Biology Staff
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Randomization, Bootstrap and Monte Carlo Methods in Biology

open access: yes, 1997
Preface to the Second Edition Preface to the First Edition Randomization The Idea of a Randomization Test Examples of Randomization Tests Aspects of Randomization Testing Raised by the Examples Sampling the Randomization Distribution or Systematic ...
B. Manly
semanticscholar   +1 more source

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