Results 71 to 80 of about 3,856,732 (267)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Correction: Cannibalism, Kuru, and Mad Cows: Prion Disease As a "Choose-Your-Own-Experiment" Case Study to Simulate Scientific Inquiry in Large Lectures. [PDF]
PLOS Biology Staff
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From systems biology to synthetic biology [PDF]
Mol Syst Biol. 1: 2005.0032 If each of us conveys our idiosyncratic view of the elephant, then we, in communion, can imagine its wholeness (Ireland, 1997). An analogous process elucidates Molecular Systems Biology (MSB) and this journal is dedicated to it. The work of a scientist/engineer (seer for short) consists of discovery, modeling, perturbation,
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Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Byline: T. Srinivasan Introduction Electrons are one of the fundamental particles postulated in physics and one of the early evolutes after the big bang, when universe started to expand and evolve into galaxies and star systems. Electrons exist in all matter, both as bound electrons and as free electrons.
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Synthetic biology: putting synthesis into biology
AbstractThe ability to manipulate living organisms is at the heart of a range of emerging technologies that serve to address important and current problems in environment, energy, and health. However, with all its complexity and interconnectivity, biology has for many years been recalcitrant to engineering manipulations.
Liang, Jing, Luo, Yunzi, Zhao, Huimin
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Acknowledgement to Reviewers of Biology in 2017
Peer review is an essential part in the publication process, ensuring that Biology maintains high quality standards for its published papers. In 2017, a total of 50 papers were published in the journal.[...]
Biology Editorial Office
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Systems biology versus molecular biology [PDF]
Molecular biology and systems biology provide answers to the same questions, but the answers are quite different for the two approaches and are, on the surface, unrelated. The molecular biological answers are arguably more fundamental and are unique, but alternative systems biology answers are possible – consider the two systems-level answers to the ...
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