Results 171 to 180 of about 657,944 (323)

Synthetic biology meets neuromorphic computing: towards a bio-inspired olfactory perception system

Kevin Max, Larissa Sames, Shimeng Ye, Jan Steinkühler, Federico Corradi   +4 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

An Analysis of the Governance, Ethical, Legal, and Social Implications of Biocomputing. [PDF]

Sci Eng Ethics
Sirbu RA, Floridi L.
europepmc   +1 more source

Models in Biology: Mathematics, Statistics and Computing. By D. Brown and P. Rothery. Pp. 688. John Wiley and Sons Ltd, 1993. £23.95 paperback. ISBN 0471 93322 8 [PDF]

, 1994
R. H. S. Carpenter
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Editorial

Engineering Biology, 2017
Richard I Kitney, Chueh Loo Poh
doaj   +1 more source

Conformation-programmed DNA computing. [PDF]

Sci Adv
Ling Q, Li B, Feng Y, Yang J, Wang S, Li S, Zhang C.   +6 more
europepmc   +1 more source

Scaling Genomics Data Processing with Memory-Driven Computing to Accelerate Computational Biology [PDF]

, 2020
Matthias Becker, Umesh Worlikar, Shobhit Agrawal, Hartmut Schultze, Thomas Ulas, Sharad Singhal, Joachim L. Schultze   +6 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

CryoJAX: a cryo-electron microscopy image-simulation library in JAX. [PDF]

Acta Crystallogr D Struct Biol
O'Brien MJ, Silva-Sánchez D, Woollard G, Je K, Hanson SM, Needleman DJ, Cossio P, Thiede EH, Astore MA.   +8 more
europepmc   +1 more source