Results 261 to 270 of about 10,694,180 (354)

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Epidemiological and Histopathological Characteristics of Fetuses with Congenital Disorders: A Study in Greece. [PDF]

Biology (Basel)
Nteli D, Nteli M, Konstantinidis K, Ouzounidou M, Theotokis P, Manthou ME, Dermitzakis I, Miliara X, Gouta C, Angelidou S, Miliaras D, Meditskou S.   +11 more
europepmc   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

A physical model links structure and function in the plant immune system. [PDF]

Proc Natl Acad Sci U S A
Weiner BG, Märkle H, Laderman E, Demirjian C, Bergelson J.   +4 more
europepmc   +1 more source

A general method for near-infrared photoswitching in biology, demonstrated by the >700 nm photocontrol of GPCR activity in brain slices [PDF]

Benedikt Baumgartner, Viktorija Glembockyte, Alberto J. Gonzalez-Hernandez, Abha Valavalkar, Robert J. Mayer, Lucy L. Fillbrook, Adrian Müller‐Deku, Jinhua Zhang, Florian Steiner, Christoph Groß, Martin Reynders, Hermany Munguba, Anisul Arefin, Armin R. Ofial, Jonathon E. Beves, Theobald Lohmueller, Benjamin Dietzek‐Ivanšić, Johannes Broichhagen, Philip Tinnefeld, Joshua Levitz, Oliver Thorn‐Seshold   +20 more
openalex   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Morphology and phylogeny of the centrohelid heliozoans Raphidocystidae and their ability to consume cyanobacteria. [PDF]

PLoS One
Zagumyonnyi DG, Gong Y, Huo D, Tikhonenkov DV.   +3 more
europepmc   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Advancing archaeal research through FAIR resource and data sharing, and inclusive community building. [PDF]

Commun Biol
Ithurbide S, Buan N, Schulze S.
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source