Results 281 to 290 of about 10,748,107 (348)

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

Visual impairment in any eye adversely affects quality of life: Psychometric validation of the Malay NEI VFQ-25. [PDF]

PLoS One
Loke JY, Rampal S, Che Hamzah J, Lim YW, Kamalden TA.   +4 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

General biology

, 1886
William T. Sedgwick, Edmund B. Wilson
openaire   +3 more sources

Expectations for papers performing Mendelian randomization analyses. [PDF]

PLoS Genet
Williams SM, Tang H, Cooper GM, O'Donnell-Luria A, Girirajan S, Dudley AM, Goriely A, Kutalik Z, Zhu X, Sirugo G, Epstein MP.   +10 more
europepmc   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

Challenges and opportunities in systems biology education. [PDF]

Endocr Relat Cancer
Didier J, Croce S, Bayoumi S, Valceschini E, Escoffier H, Gonzalez E, Kishk A, Badkas A, De Landtsheer S, Sauter T.   +9 more
europepmc   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

THE VALIDITY OF GENERAL BIOLOGY LEARNING EQUIPMENT BASED ON CASE METHOD AND PROJECT BASED LEARNING

Dina Handayani, Martina Restuati, Nanda Pratiwi, Ummu Haniyyah, Rahmad H. Gultom, Sanimah Sanimah   +5 more
openalex   +1 more source

Peptide bonds strike back. [PDF]

IUCrJ
Chari A.
europepmc   +1 more source