Results 71 to 80 of about 10,999,138 (370)

Integrative Systems Biology Visualization with MAYDAY

Journal of Integrative Bioinformatics, 2010
Visualization is pivotal for gaining insight in systems biology data. As the size and complexity of datasets and supplemental information increases, an efficient, integrated framework for general and specialized views is necessary.
Symonsy Stephan, Zipplies Christian, Battke Florian, Nieselt Kay   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

THE BIOLOGICAL AND STRUCTURAL CHARACTERIZATION OF TRANSFERABLE BACTEROIDES R PLASMIDS [PDF]

, 1979
In this literature review I will briefly describe the general biology of transferable antibiotic resistance in bacteria, the genetic elements involved (plasmids) and several specific plasmid associated phenotypes.
Welch, Rodney A.
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Integrated Analytical System for Clinical Single‐Cell Analysis

Advanced Science, 2022
High‐dimensional analyses of cancers can potentially be used to better define cancer subtypes, analyze the complex tumor microenvironment, and perform cancer cell pathway analyses for drug trials.
Hannah M. Peterson, Lip Ket Chin, Yoshi Iwamoto, Juhyun Oh, Jonathan C. T. Carlson, Hakho Lee, Hyungsoon Im, Ralph Weissleder   +7 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Phylogenetic Diversity and Extracellular Enzymatic Activities of Yeasts and Yeast-Like Fungi Isolated From Qualea grandiflora (Vochysiaceae) in Cerrado Areas in Northern Minas Gerais, Brazil

International Journal of Microbiology
The Brazilian savannah, Cerrado, a Brazilian phytophysiognomy, is an entire biome that contains as well as other Brazilian ecosystems, a vast biodiversity of microorganisms associated with native plants.
Jaqueline Silva Vieira, Dailane Amaral de Almeida, Rodrigo Oliveira Pessoa, Magno Augusto Zazá Borges, Henrique Maia Valério   +4 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

PROFESSION OF BIOLOGY TEACHER IN UKRAINE: STATISTICAL CHARACTERISTICS

Неперервна професійна освіта: теорія та практика
In the context of reforming general secondary education, it is important to identify and analyze the changes occurring in the human resources of the general secondary education system under the influence of various factors, particularly the martial law ...
Lidiia Vashchenko
doaj   +1 more source

Urban fragmentation leads to lower floral diversity, with knock-on impacts on bee biodiversity

Scientific Reports, 2020
Bees and flowering plants are two closely interacting groups of organisms. Habitat loss and fragmentation associated with urbanisation are major threats to both partners.
Panagiotis Theodorou, Sarah-Christine Herbst, Belinda Kahnt, Patricia Landaverde-González, Lucie M. Baltz, Julia Osterman, Robert J. Paxton   +6 more
doaj   +1 more source