Results 71 to 80 of about 10,818,784 (270)

Megadomains and superloops form dynamically but are dispensable for X-chromosome inactivation and gene escape

open access: yesNature Communications, 2018
The mammalian inactive X-chromosome (Xi) is organized into megadomains and superloops directed by the noncoding loci, Dxz4 and Firre. Here the authors provide evidence that megadomains do not precede Xist expression or Xi gene silencing, and suggest that
John E. Froberg   +4 more
doaj   +1 more source

Urban fragmentation leads to lower floral diversity, with knock-on impacts on bee biodiversity

open access: yesScientific Reports, 2020
Bees and flowering plants are two closely interacting groups of organisms. Habitat loss and fragmentation associated with urbanisation are major threats to both partners.
Panagiotis Theodorou   +6 more
doaj   +1 more source

PRC1 collaborates with SMCHD1 to fold the X-chromosome and spread Xist RNA between chromosome compartments

open access: yesNature Communications, 2019
The inactive X (Xi)-specific S1/S2 chromosome compartments are merged by SMCHD1, but how the S1/S2 structure is constructed is unclear. The authors find that PRC1 drives the formation of S1/S2s and that the stepwise folding process of the Xi facilitates ...
Chen-Yu Wang   +4 more
doaj   +1 more source

Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents

open access: yesNeoplasia: An International Journal for Oncology Research, 2012
A number of small-molecule poly (ADP-ribose) polymerase (PARP) inhibitors are currently undergoing advanced clinical trials. Determining the distribution and target inhibitory activity of these drugs in individual subjects, however, has proven ...
Thomas Reiner   +7 more
doaj   +1 more source

Systems Biology — the Broader Perspective

open access: yesCells, 2013
Systems biology has two general aims: a narrow one, which is to discover how complex networks of proteins work, and a broader one, which is to integrate the molecular and network data with the generation and function of organism phenotypes.
Jonathan Bard
doaj   +1 more source

Africa: the FBA connection [PDF]

open access: yes, 1986
Since its inception in the 1930's the Freshwater Biological Association at Windermere, England has been involved in research on African lakes and rivers.
Fryer, G., Talling, J.F.
core  

THE BIOLOGICAL AND STRUCTURAL CHARACTERIZATION OF TRANSFERABLE BACTEROIDES R PLASMIDS [PDF]

open access: yes, 1979
In this literature review I will briefly describe the general biology of transferable antibiotic resistance in bacteria, the genetic elements involved (plasmids) and several specific plasmid associated phenotypes.
Welch, Rodney A.
core   +1 more source

Gauge field, strings, solitons, anomalies and the speed of life

open access: yes, 2014
It's been said that "mathematics is biology's next microscope, only better; biology is mathematics' next physics, only better". Here we aim for something even better. We try to combine mathematical physics and biology into a picoscope of life.
Niemi, Antti J.
core   +1 more source

Transfer learning enables predictions in network biology

open access: yesNature, 2023
Christina V. Theodoris   +10 more
semanticscholar   +1 more source

Experiment in Self-Instruction in General Biology [PDF]

open access: yes, 1962
Author Institution: Department of Biology and Department of Psychology, Oberlin College, Oberlin ...
Atta, Ellis L. Van, Kormondy, Edward J.
core  

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