Results 71 to 80 of about 10,748,107 (348)

Integrative Systems Biology Visualization with MAYDAY

open access: yesJournal of Integrative Bioinformatics, 2010
Visualization is pivotal for gaining insight in systems biology data. As the size and complexity of datasets and supplemental information increases, an efficient, integrated framework for general and specialized views is necessary.
Symonsy Stephan   +3 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Mucosal and Cutaneous Human Papillomavirus Infections and Cancer Biology

open access: yesFrontiers in Oncology, 2019
Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been listed so far.
T. Gheit
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Nano-palladium is a cellular catalyst for in vivo chemistry

open access: yesNature Communications, 2017
Palladium (Pd) is a well-known catalyst in organic chemistry but its use in nanomedicine is limited. Here, the authors design a Pd nanoparticle that triggers the activation of an antitumour prodrugin vivo, which shows efficacy and improves toxicity ...
Miles A. Miller   +5 more
doaj   +1 more source

The Inclusion of False, Falsified, and Falsifiable Data that Favor an Evolutionary Worldview in the High School Science Curriculum of Public and Private Schools in the Philippines [PDF]

open access: yes, 2015
This paper examines a curricular issue in general within public and private high schools in the Philippines. This paper presents six known and documented errant points found in textbooks that promote an evolutionary worldview and are commonly found in ...
Smith, Jerry F
core   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens

open access: yesNature Communications, 2018
Diagnostic tests need optimization to avoid invasive and costly repeated biopsies. Here the authors present an antibody-DNA barcoding approach where harvested single cells can be re-stained through custom oligonucleotide-fluorophore conjugates, enabling ...
Randy J. Giedt   +6 more
doaj   +1 more source

Developing a Web-Based Learning (E-Learning) in General Biology Subjects with Joomla Program

open access: yesBiosfer, 2018
Web-based learning has been widely used as learning resources. Developing these learning resources is believed to provide beneficial for students. Therefore, this research was aimed to develop a web-based learning source for General Biology Course.
Muhamad Nurdin Matondang Seribulan   +2 more
doaj   +1 more source

Negative Energy: Why Interdisciplinary Physics Requires Multiple Ontologies

open access: yes, 2013
Much recent work in physics education research has focused on ontological metaphors for energy, particularly the substance ontology and its pedagogical affordances.
Dreyfus, Benjamin W.   +5 more
core   +1 more source

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