Results 61 to 70 of about 662,153 (301)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

CONTRIBUIÇÃO DA FILOSOFIA DA MICROBIOLOGIA PARA FUNDAMENTAR A ZONA RELACIONAL DO PERFIL CONCEITUAL DE VIDA

Ensaio Pesquisa em Educação em Ciências
Discute-se, neste estudo, como as reflexões da filosofia da Microbiologia podem contribuir para fundamentar a zona relacional do conceito biológico vida e os benefícios que traria para o aprendizado dos alunos em virtude de sua utilização em sala de aula.
Francisco Ângelo Coutinho, Rogério Parentoni Martins, Marcos Costa Vieira   +2 more
doaj   +1 more source

Documental analysis of Brazilian academic production about evolution teaching (1990-2010): characterization and proposals [PDF]

Investigações em Ensino de Ciências, 2013
The quantitative and qualitative increasing of researches in Science teaching imposes the periodical mapping need of scientific production about the subject, with a view to identify its own characteristics and tendencies. In this context, researches such
Caio Samuel Franciscati da Silva, Jair Lopes Junior   +1 more
doaj  

Peer-Led Team Learning in Introductory Biology and Chemistry Courses: A Parallel Approach [PDF]

, 2003
Peer-Led Team Learning has been in use in Introductory Biology and Introductory Chemistry since Fall 1999 at the University of Portland. lts effect on improved conceptual understanding, retention of students, and improvement in study skills will be ...
Houck, B., Tenney, A.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

An epistemological perspective on the didactical transposition of Gaia theory [PDF]

Investigações em Ensino de Ciências, 2001
This paper is part of larger scope project in which the scientificity of the Gaia theory is analysed, intending to contribute towards a critical appraisal or the role that such a theory might have in biology teaching and in approaching the "environment ...
Marina de Lima-Tavares, Charbel Niño El-Hani   +1 more
doaj  

Multidisciplinary teaching of Biotechnology and Omics sciences [PDF]

, 2017
In the last years, there was a great boom in the Omics fields that have developed as multidisciplinary sciences. They use laboratory techniques related to Biology and Chemistry but also Bioinformatics tools. However, the developmental progress of these
Canovas-Ramos, Francisco Miguel, Cantón, Francisco R., Cañas, Rafael A., De la Torre, Fernando, El-Azaz Ciudad, Jorge, Pascual, Belen M, Ávila, Concepción   +6 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cross-Cultural Biology Teaching Using Next-Generation Science Standards

Education Sciences
This study explored Next Generation Science Standards (NGSS) in cross-cultural biology teaching through collaborative lesson studies involving educators from the USA and the Philippines.
Jason Jimenez, Denis Dyvee Errabo
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source