Results 261 to 270 of about 613,209 (287)

Biomarkers for prostate cancer detection

Expert Review of Anticancer Therapy, 2010
Since its approval by the US FDA in 1986, prostate-specific antigen (PSA) has been employed to monitor men with a diagnosis of prostate cancer. In 1994, PSA was approved for use in prostate cancer screening and has been employed worldwide. However, due to the limited specificity of PSA for the disease, novel biomarkers are needed for detecting prostate
Amanda Beth, Reed, Dipen J, Parekh
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BIOMARKERS Occurence, Utility, and Detection

Analytical Chemistry, 1988
The study of natural products in plants, animals, bacteria, fungi, and other living systems has long been of interest to chemists, biochemists, and analytical chemists. Generally, however, these scientists are concerned only with the isolation and identification of compounds present in living systems.
R. Paul Philp, Jung Nan Oung
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Bioinformatics: Biomarkers of early detection

Cancer Biomarkers, 2011
Capturing, sharing, and publishing cancer biomarker research data are all fundamental challenges of enabling new opportunities to research and understand scientific data. Informatics experts from the National Cancer Institute's (NCI) Early Detection Research Network (EDRN) have pioneered a principled informatics infrastructure to capture and ...
Daniel J, Crichton, Chris A, Mattmann, Mark, Thornquist, Kristen, Anton, J Steven, Hughes   +4 more
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Advances in biomarker detection: Alternative approaches for blood-based biomarker detection

2019
In the clinical setting, a blood sample is typically the starting point for biomarker search and discovery. Mass spectrometry (MS) is a highly sensitive and informative method for characterizing a very wide range of metabolites and proteins and is therefore a potentially powerful tool for biomarker discovery.
Miguel, Rosado, Rafael, Silva, Mariana, G Bexiga, John, G Jones, Bruno, Manadas, Sandra I, Anjo   +5 more
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Graphene-Based Protein Biomarker Detection

Bioanalysis, 2015
An ability to detect and quantify protein molecules, harbingers of specific pathologies, potentially underpins both early disease diagnosis and an assessment of treatment efficacy. However, the specific detection of a particular protein biomarker in a complex environment is by no means an easy task and requires a progressive improvement in sensor ...
Amol V, Patil, Flavio B, Fernandes, Paulo R, Bueno, Jason J, Davis   +3 more
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Biomarkers for Prostate Cancer Detection

Journal of Urology, 2007
The limitations of prostate specific antigen as a biomarker for prostate cancer screening, characterized by low sensitivity for acceptable false-positive rates, are well known. New markers that differentiate indolent from aggressive cancers to decrease potential the over treatment of prostate cancer are needed.
Dipen J, Parekh, Donna Pauler, Ankerst, Dean, Troyer, Sudhir, Srivastava, Ian M, Thompson   +4 more
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An OMIC Biomarker Detection Algorithm TriVote and its Application in Methylomic Biomarker Detection

Epigenomics, 2018
Transcriptomic and methylomic patterns represent two major OMIC data sources impacted by both inheritable genetic information and environmental factors, and have been widely used as disease diagnosis and prognosis biomarkers.Modern transcriptomic and methylomic profiling technologies detect the status of tens of thousands or even millions of probing ...
Cheng, Xu, Jiamei, Liu, Weifeng, Yang, Yayun, Shu, Zhipeng, Wei, Weiwei, Zheng, Xin, Feng, Fengfeng, Zhou   +7 more
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Biomarkers detection with magnetoresistance-based sensors

Biosensors and Bioelectronics, 2020
Biosensing platforms for detecting and quantifying biomarkers have played an important role in the past decade. Among them, platforms based on magnetoresistance (MR) sensing technology are attractive. The resistance value of the material changes with the externally applied magnetic field is the core mechanism of MR sensing technology.
Chunhui, Ren, Qiaoge, Bayin, Shilun, Feng, Yusheng, Fu, Xing, Ma, Jinhong, Guo   +5 more
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Systems biology of cancer biomarker detection

Cancer Biomarkers, 2013
Cancer systems-biology is an ever-growing area of research due to explosion of data; how to mine these data and extract useful information is the problem. To have an insight on carcinogenesis one need to systematically mine several resources, such as databases, microarray and next-generation sequences. This review encompasses management and analysis of
Sanga, Mitra, Smarajit, Das, Jayprokas, Chakrabarti   +2 more
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Developing recombinant antibodies for biomarker detection

Cancer Biomarkers, 2010
Monoclonal antibodies (mAbs) have an essential role in biomarker validation and diagnostic assays. A barrier to pursuing these applications is the reliance on immunization and hybridomas to produce mAbs, which is time-consuming and may not yield the desired mAb.
Cheryl L, Baird, Christopher J, Fischer, Noah B, Pefaur, Keith D, Miller, Jacob, Kagan, Sudhir, Srivastava, Karin D, Rodland   +6 more
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