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Nucleoprotein Assemblies for Cellular Biomarker Detection

Nano Letters, 2006
In this report, we have used DNA Y-junctions as fluorescent scaffolds for EcoRII methyltransferase-thioredoxin (M.EcoRII-Trx) fusion proteins. Covalent links between the DNA scaffold and the methyltransferase were formed at preselected sites on the scaffold containing 5FdC.
Elizabeth M, Singer, Steven S, Smith
openaire   +2 more sources

Nanosensors in Biomarker Detection

2019
A biomarker is an indicator or molecular signature that is observed in normal bodily biological processes or disease conditions. Biomarkers exist in various forms, such as proteins, peptides, antibodies, cells, metabolites, hormones, lipids, and enzymes. Developing sensitive methods for the detection of diseases at an earlier stage via these structures
Burcin, Bozal-Palabiyik   +2 more
openaire   +1 more source

Raman based hepatocellular carcinoma biomarker detection

2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2011
Highly sensitive and selective biomarker detection is required for early detection of hepatocellular carcinoma (HCC). Disease progression has been shown to correlate with specific fucosylation of a validated HCC serum glycoprotein biomarker, alpha-fetoprotein (AFP) Carbohydrate binding proteins, such as lectins, can be used as diagnostic indicators for
M A, Santiago-Cordoba   +3 more
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C. difficile biomarkers, pathogenicity and detection

Clinica Chimica Acta
Clostridioides difficile infection (CDI) is the main etiologic agent of antibiotic-associated diarrhea. CDI contributes to gut inflammation and can lead to disruption of the intestinal epithelial barrier. Recently, the rate of CDI cases has been increased. Thus, early diagnosis of C.
Sepideh, Ziaei Chamgordani   +2 more
openaire   +2 more sources

Malaria detection using breath biomarkers

Medical Journal of Australia, 2016
Amalia Z, Berna   +2 more
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Electrochemical detection of cervical cancer biomarkers

Clinica Chimica Acta
Cervical cancer (CC) is the fourth most common cancer among women worldwide, following breast, colorectal, and lung cancers. Each year, it accounts for approximately 600,000 new cases and 340,000 deaths. Early-stage cervical cancer is treatable with surgery and chemoradiotherapy (CCRT). However, treatment for metastatic cervical cancer is limited, with
Tummala, Anusha   +4 more
openaire   +2 more sources

Aptasensors for Biomarker Detection

Journal of Analytical Chemistry, 2022
Liu He   +5 more
openaire   +1 more source

Biomarker Detection in the Wastewater Phantom

Journal of Biophotonics
ABSTRACTResearch trends are focused on developing solutions that monitor public health utilizing sewage surveillance, as wastewater can provide valuable information on the presence of specific biomarkers. Such information can serve as an indication of immune response at the community level, delivering a noninvasive measure of e.g., vaccination ...
Adam Władziński   +5 more
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BIOMARKER- THE MOLECULAR DETECTIVE

This comprehensive article delves into the multifaceted realm of biomarkers, offering an exhaustive exploration of their definition, classification, and pivotal roles in diverse fields. The molecular detectives, as biomarkers are aptly termed, provide measurable insights into physiological and pathological processes, therapeutic responses, and ...
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Detecting Circulating miRNA Biomarkers

Genetic Engineering & Biotechnology News, 2016
Jordan Plieskatt, Daniel Pregibon
openaire   +1 more source

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