Results 51 to 60 of about 613,209 (287)

Chemoenzymatic Probes for Detecting and Imaging Fucose-α(1-2)-galactose Glycan Biomarkers [PDF]

, 2012
The disaccharide motif fucose-α(1-2)-galactose (Fucα(1-2)Gal) is involved in many important physiological processes, such as learning and memory, inflammation, asthma, and tumorigenesis.
Becker D. J., Blixt O., Blixt O., Chang C.-F., Chang W.-W., Chithra Krishnamurthy, Clark P. M., David F. Smith, Delves P. J., Hanson S. R., Jean-Luc Chaubard, Khidekel N., Kim Y., Laughlin S. T., Lee J. S., Linda C. Hsieh-Wilson, Manimala J. C., Manimala J. C., Miyake M., Murrey H. E., Murrey H. E., Peracaula R., Pohle W., Rexach J. E., Schröder F. H., Tanaka Y., Tiunova A. A., Wen Yi, Yi W., Zhang S., Zheng T.   +30 more
core   +3 more sources

Serum Biomarkers for Detecting Ectopic Pregnancy [PDF]

Clinical Obstetrics & Gynecology, 2012
Unless an ectopic pregnancy is visible by ultrasound, diagnosis can be a challenge. Differentiating ectopic pregnancies from intrauterine pregnancies can be impossible without intervention or follow-up. This poses a clinical dilemma to the practitioner given the inherent danger to the mother of tubal rupture of an ectopic pregnancy versus the fear of ...
Mary E, Rausch, Kurt T, Barnhart
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Validation of a Multivariate Serum Profile for Epithelial Ovarian Cancer Using a Prospective Multi-Site Collection [PDF]

, 2010
In previous studies we described the use of a retrospective collection of ovarian cancer and benign disease samples, in combination with a large set of multiplexed immunoassays and a multivariate pattern recognition algorithm, to develop an 11-biomarker ...
Beth Y. Karlan, Brian C. Mansfield, Brigitte E. Miller, Eva Chalas, Glenn E. Bigsby, Greg P. Bertenshaw, James F. Barter, James P. Mapes, James W. Orr, Jinghua Zhao, Katharine J. Bergstrom, Laurie L. Stephen, Lynda D. Roman, Michael E. McCollum, Partha Seshaiah, Paul A. DiSilvestro, Ping F. Yip, Robert W. Holloway, Ronald D. Alvarez, Suraj Amonkar, Tzong-Hao Chen   +20 more
core   +1 more source

Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]

, 2014
BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A, Loo, Rachel R Ogorzalek, Shen, Sean, Wanner, Ina-Beate   +3 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Molecular characterization and subtype analysis of Blastocystis sp. in captive wildlife in Henan, China

Parasite
Blastocystis sp. is a zoonotic intestinal protozoan that is ubiquitous globally, residing in the gastrointestinal tracts of both humans and various animals.
Cui Zhaohui, Huang Xiyao, Zhang Sulan, Li Kaifang, Zhang Aili, Li Qichen, Zhang Yutong, Li Junqiang, Qi Meng   +8 more
doaj   +1 more source

Towards Understanding Non-Infectious Growth-Rate Retardation in Growing Pigs

Proteomes, 2019
For growth-rate retardation in commercial growing pigs suffering from non-infectious diseases, no biomarker is available for early detection and prevention of the condition or for the diagnosis of affected animals.
Ana M. Gutiérrez, Juan Sotillo, Sarah Schlosser, Karin Hummel, Ingrid Miller   +4 more
doaj   +1 more source

Modular Micro Raman Reader Instrument for Fast SERS-Based Detection of Biomarkers

Micromachines, 2022
Sensitive detection of biomarkers is very critical in the diagnosis, management, and monitoring of diseases. Recent efforts have suggested that bioassays using surface-enhanced Raman scattering as a signal read-out strategy possess certain unique ...
Jamison Duckworth, Alexey V. Krasnoslobodtsev   +1 more
doaj   +1 more source

Biomarker Detection in Association Studies: Modeling SNPs Simultaneously via Logistic ANOVA [PDF]

, 2014
In genome-wide association studies, the primary task is to detect biomarkers in the form of Single Nucleotide Polymorphisms (SNPs) that have nontrivial associations with a disease phenotype and some other important clinical/environmental factors. However,
Hu, Jianhua, Huang, Jianhua, Jung, Yoonsuh   +2 more
core   +2 more sources