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Identification and immunoassay of biomarkers associated with T cell exhaustion in systemic lupus erythematosus. [PDF]
Front ImmunolZheng Y +6 more
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Integrating multi-cohort machine learning and clinical sample validation to explore peripheral blood mRNA diagnostic biomarkers for prostate cancer. [PDF]
Cancer Cell IntZhong X +6 more
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Relationships between blood pressure indicators and fluid biomarkers of brain aging in functionally intact older adults. [PDF]
Alzheimers Res TherVandeBunte AM +13 more
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Biomarkers: to be or not to be
Annals of the Rheumatic Diseases, 2020We read with great interest the article by van den Hoogen et al 1 describing galectin-9 (Gal-9) as a novel, easy-to-measure biomarker for the interferon (IFN) signature in systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). We support the views expressed by the authors that IFN signature is an important biomarker in disease activity
Lars Rönnblom, Sule Yavuz
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2015
Biomarkers are key tools and can provide crucial information on the complex cascade of events and molecular mechanisms underlying traumatic brain injury (TBI) pathophysiology. Obtaining a profile of distinct classes of biomarkers reflecting core pathologic mechanisms could enable us to identify and characterize the initial injury and the secondary ...
MONDELLO, STEFANIA, Hayes, Ronald L.
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Biomarkers are key tools and can provide crucial information on the complex cascade of events and molecular mechanisms underlying traumatic brain injury (TBI) pathophysiology. Obtaining a profile of distinct classes of biomarkers reflecting core pathologic mechanisms could enable us to identify and characterize the initial injury and the secondary ...
MONDELLO, STEFANIA, Hayes, Ronald L.
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Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
Clinical pharmacology and therapy, 2001genome are dramatically reshaping the research and development pathways for drugs, vaccines, and diagnostics. The growth in the number of molecular entities entering the drug development pipeline has accelerated as a consequence of powerful discovery and
A. Atkinson +11 more
semanticscholar +1 more source
Current Opinion in Organ Transplantation, 2013
As the induction and maintenance of donor-specific tolerance is a central aim in solid organ transplantation, it is essential that clinicians are able to identify and monitor tolerance accurately and reliably. This review highlights recent advances in defining sets of biomarkers in noninvasive samples that may guide minimization and withdrawal of ...
Gökmen, Refik, Hernandez Fuentes, Maria
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As the induction and maintenance of donor-specific tolerance is a central aim in solid organ transplantation, it is essential that clinicians are able to identify and monitor tolerance accurately and reliably. This review highlights recent advances in defining sets of biomarkers in noninvasive samples that may guide minimization and withdrawal of ...
Gökmen, Refik, Hernandez Fuentes, Maria
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2019
Aggressive behavior exerts an enormous impact on society remaining among the main causes of worldwide premature death. Effective primary interventions, relying on predictive models of aggression that show adequate sensitivity and specificity are currently lacking.
Vassilios Fanos +8 more
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Aggressive behavior exerts an enormous impact on society remaining among the main causes of worldwide premature death. Effective primary interventions, relying on predictive models of aggression that show adequate sensitivity and specificity are currently lacking.
Vassilios Fanos +8 more
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Biomarkers in pediatrics: Children as biomarker orphans
PROTEOMICS – Clinical Applications, 2010AbstractBiomarkers have enormous potential to improve patient care by establishing tests of diagnosis, prognosis, and treatment effects. Successfully translating a biomarker from discovery to clinical application demands high‐quality discovery research and high‐quality clinical studies for biomarker validation; however, there are additional challenges ...
Allen D. Everett, William J. Savage
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2000
Earthworms are believed to be so-called key species within ecosystems and are often exposed to a wide range of anthropogenic compounds released to the terrestrial environment. As a consequence, they may suffer from the toxicity of these compounds. For these and other reasons, earthworms have been used extensively in ecotoxicological studies.
Scott-Fordsmand, J. J., Weeks, J. M.
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Earthworms are believed to be so-called key species within ecosystems and are often exposed to a wide range of anthropogenic compounds released to the terrestrial environment. As a consequence, they may suffer from the toxicity of these compounds. For these and other reasons, earthworms have been used extensively in ecotoxicological studies.
Scott-Fordsmand, J. J., Weeks, J. M.
openaire +3 more sources